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Romania
Citizenship:
Ph.D. degree award:
2003
Ms.
Victoria Cecilia
Cristea
PhD. Habil.
Professor
-
UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU"
Teaching staff
17
years
Personal public profile link.
Curriculum Vitae (02/10/2019)
Expertise & keywords
Electrochemical and optical sensors, biomimetic sensors, bioelectrochemistry, immuno and aptasensors, organic electrosynthesis
drug analysis, separation techniques, hyphenated techniques, spectral analysis
nanomaterials used in design of sensors, carbon nanotubes, magnetic and metallic nanoparticles
Projects
Publications & Patents
Entrepreneurship
Reviewer section
Border detection of illicit drugs and precursors by highly accurate electrosensors
Call name:
833787
2019
-
2023
Role in this project:
Partner team leader
Coordinating institution:
University of Antwerp
Project partners:
University of Antwerp (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)
Project website:
https://cordis.europa.eu/project/rcn/222634/factsheet/en
Abstract:
Combining robust sensor technologies with the inherent advantages of electrochemical strategies, nano-molecularly imprinted polymers, and multivariate and pattern data analysis, BorderSens will enable highly accurate selective detection of trace levels of illicit drugs and precursors. With borders being important gateways for the entrance of illicit drugs and their precursors, custom and border control authorities are facing pertaining challenges to detect such dangerous substances and safeguard the public. The main challenges posed by currently used on-site methods to detect illicit drugs and precursors are low accuracy, in the case of colour tests, and high cost and low portability, in the case of spectroscopic tests. In the light of a pressing need for better drug test systems at EU borders, the ultimate research aim of the BorderSens is to develop a portable, wireless single prototype device with the capability to quickly test for different types of drugs, precursors and adulterants/cutting agents, with outstanding accuracy and reduced false positives and false negatives. BorderSens will demonstrate the innovative technological solutions at seven demonstrations sites at EU borders with end-users and ensure exploitation plans guaranteeing strong impact. BorderSens brings together universities, a big manufacturer of electrochemical sensors, a specialised SME, ten end-users i.e. forensic institutes, police forces and border authorities, and a high quality external advisory board, to provide an excellent scientific-technical perspective and a straightforward exploitation route, with great impact on the safety of EU citizens.
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Pathogen Contamination Emergency Response Technologies
Call name:
EC - H2020
H2020-229396-883484
2020
-
2023
Role in this project:
Partner team leader
Coordinating institution:
UNIVERSITY OF CYPRUS
Project partners:
UNIVERSITY OF CYPRUS (CY); ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS (EL); WATER EUROPE (BE); COMMUNICATION AND INFORMATION SYSTEMS DIRECTORATE (BG); AQUA-Q AB (SE); KWR WATER B.V. (NL); ETAIRIA HYDREFSIS KAI APOCHETEFSIS THESSALONIKIS AE (EL); SUNDOSOFT LTD (KR); UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA (RO); MINISTRY OF INTERIOR (CY); Korea Institute of Science and Technology (KR); ELLINIKI OMADA DIASOSIS SOMATEIO (EL); NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA (EL); MicroLAN (NL); CETAQUA, CENTRO TECNOLOGICO DEL AGUA, FUNDACION PRIVADA (ES); AYUNTAMIENTO DE GRANADA (ES); FUNDACIO EURECAT (ES); SATWAYS - PROIONTA KAI YPIRESIES TILEMATIKIS DIKTYAKON KAI TILEPIKINONIAKON EFARMOGON ETAIRIA PERIORISMENIS EFTHINIS EPE (EL); COLLABORATING CENTRE ON SUSTAINABLE CONSUMPTION AND PRODUCTION GGMBH (DE); STICHTING WATERNET (NL); FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE); PHOEBE RESEARCH AND INNOVATION LTD (CY); ENGINEERING - INGEGNERIA INFORMATICA SPA (IT)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA (RO)
Project website:
Abstract:
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Design sensing platforms for detection and quantification of biomarkers involved in neurological disorders
Call name:
Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-0460
2015
-
2017
Role in this project:
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO)
Project website:
http://www.granturi.umfcluj.ro/BIO-NEURO-SENS
Abstract:
Neurological disorders are numerous, diverse, frequently severe, affecting a large portion of the world’s population, with challenges in their diagnosis and treatment. The current project proposes the development of a global strategy for designing (bio)sensors, involving an ultrasensitive electrochemical setup based on a specific and selective nanoplatform capable of simultaneous detection of some biomarkers involved in neurological disorders. The originality of the proposed project resides from the use of electroanalytical methods involving electrodes modified in a controlled and optimized way with a novel association of nanomaterials with bioelements. Various strategies are envisaged for the functionalization of different types of electrodes and the use of various nanomaterials, design of new and innovative way that will allow their immobilization. The obtainment of the completely functional nanoplatforms will be followed by the optimum immobilization of the bioelements (enzyme, antibody, aptamer) will be determined, assuring highly specific detection. After the complete characterization of the elaborated sensors in terms of properties and performances, their application for real samples analyses will be tested, as a first step in development of point-of-care devices.
The success of the project could assure an early diagnosis of neurological disorders with improvement in the health of the population.
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AMPEROMETRIC IMMUNOSENSOR FOR OVARIAN AND UTERINE CANCER BIOMARKERS
Call name:
Exploratory Research Projects - PCE-2011 call
PN-II-ID-PCE-2011-3-0355
2011
-
2016
Role in this project:
Key expert
Coordinating institution:
Universitatea de Medicina si Farmacie ˝Iuliu Hatieganu˝ Cluj-Napoca
Project partners:
Universitatea de Medicina si Farmacie ˝Iuliu Hatieganu˝ Cluj-Napoca (RO)
Affiliation:
Project website:
http://www.granturi.umfcluj.ro/id338
Abstract:
The MUC1 gene encodes a type-I transmembrane glycoprotein that is expressed on the apical surface of most simple epithelia, including mammary gland, female reproductive tract, lung, kidney, stomach, gall bladder, and pancreas as well as some non-epithelial cell types.
Recent immunological studies suggest that MUC1 is a potential marker and a prognosis factor in diagnosis of ovarian cancer and endometriosis.
It is proposed the elaboration of a novel series of immunosensors based on MUC1 and tumor MUC1 proteins, which can be a specific and sensitive alternative to currently more or less invasive, immunohistochemical methods actually used. Once the tumor proteins in blood successfully detected, will be followed by the design and construction of a noninvasive, specific and sensitive diagnostic device for biological fluids.
The main objectives are: 1). Development of new immunosensing devices; a. Electroactive surface design (fabrication of gold and carbon based screen-printed electrodes functionalized by thiolic compounds, carbon nanotubes, graphenes as nanobiolabels); b. Bioelement design (choice of antibodies and/or aptamers); c. Immunosensor development by different immobilization methods (biotin-avidin, selfassembling, conducting polymers); 2). Electroanalytical characterization of the new immunosensors (electrode surface characterization, electroanalytical performances); 3). Immunoelectrochemical method elaboration and prevalidation (design and optimization of the immun
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Call name:
Premierea obtinerii atestatului de abilitare - Competitia 2015
PN-II-RU-ABIL-2015-2-0008
2015
-
Role in this project:
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO)
Project website:
Abstract:
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FUNCTIONALIZED NANOMATERIALS WITH CHROMO AND FLUOROPHORES AND NANOSTRUCTURED PLATFORMS FOR BIOSENSORS APPLIED IN PHARMACEUTICAL AND BIOMEDICAL FIELDS
Call name:
Programul de actiuni Integrate Romania-Franta (bilaterale)
PN-II-CT-RO-FR-2014-2-0008
2014
-
Role in this project:
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO); Universite Joseph Fourier (FR)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO)
Project website:
Abstract:
The aim of this project is to obtain supramolecular nanomaterials functionalized with chromophores and fluorescent compounds and nanostructured platform for the development of biosensors with possible applications in the detection of biomedical and pharmaceutical compounds. For this purpose new nanostructured surfaces with photoelectrochemical properties will be develop by combining chromophores or fluorophores with new nanomaterials. Several molecules are taken into account: photosensitive transition metal complexes such as complexes of Ru(II) with pyridine having photoelectrochemical and electrochemiluminescence properties, and tetrazine derivatives, due to their fluorescent properties. Another objective of the project is to obtain nanostructured platforms by nanospheric lithography for the controlled immobilization of biomolecules and rational design of biosensors, with possible applications in biomedical analysis. Modified electrodes with graphene, cyclodextrins and polymer films for detection and simultaneous determination of ascorbic acid, uric acid and dopamine in pharmaceutical and biological samples will also develop. This collaboration will enable the development of new research directions on the topic of biosensors using the scientific skills of each team.
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FILE DESCRIPTION
DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects
[T: 0.4194, O: 392]