BrainMap

Mr. Tiberiu Szoke-Nagy

Researcher

Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Other affiliations

PhD Student - UNIVERSITATEA BABES BOLYAI (Romania)

Researcher

Web of Science ResearcherID: C-2823-2012

Expertise & keywords

Pathogenic microorganisms’ rapid detection and identification using high sensitive Raman spectroscopy Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-0862 2015 - 2017

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Project website: http://www.itim-cj.ro/PNCDI/ru381/

Abstract:

The bio-sensing for bacteria detection is currently explored by using various sensing materials and approaches but it is still a challenge to find an alternative to the conventional protocols, based on microorganisms’ cultivation. This project proposal provides an ultrasensitive and selective, but simple, rapid and inexpensive bacteria detection and identification method by using a receptor-free and innovative immobilization principle of the biomass. Raman spectroscopy, which combines the selectivity of the method with the sensitivity of the surface-enhanced Raman scattering effect (SERS), is used in correlation with Principle Component Analysis (PCA) in order to develop biosensors for pathogenic microorganisms. Most common pathogenic bacteria will be tested by applying an original immobilization protocol and the in situ synthesis method of the SERS-active nanostructures. The specific molecular information gathered from the spectroscopic data will be uploaded and analyzed by means of advanced statistical methods, with the final goal of creating an appropriate protocol which will be used on complex biological samples. The rapid pathogens identification and differentiation between multiple species, down to strain level will be carried out by means of SERS-PCA bio-sensing. Furthermore, the efficiency of multiple classes of antibiotics on bacteria viability will be investigated by SERS in order to obtain rapid and precise diagnostic and targeted treatment.

Methodological guide for monitoring antibiotic residues and antimicrobial resistance in the environment as a supporting instrument for an enhanced quality management of surface waters and groundwater. Call name:
EEA Grants 3499/2015 -

Role in this project: Key expert

Coordinating institution: INSTITUTUL DE CERCETARI BIOLOGICE CLUJ FILIALA A INCDSB BUCURESTI

Project partners:

Affiliation:

Project website: http://Http://enviroamr.ro

Abstract:

The EnviroAMR project rose awareness on the fact that antibiotics and antimicrobial resistant microorganisms are considered novel classes of pollutants in the environment with major consequences on the health of humans, animals and plants. The EnviroAMR project has proposed a methodological guide for a standardized monitorization of antibiotics and antibiotic resistance in the environment through a chemical and biological (phenotypic, genotypic, metagenomic) approach together with techniques of antibiotics/antibiotic resistance mitigation in wastewaters.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects