BrainMap

Nicoleta Lupu

Dr.

Senior Researcher - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Researcher | Scientific reviewer | Manager | PhD supervisor

Curriculum Vitae (22/04/2016)

Expertise & keywords

Magnetic amorphous/nanocrystalline dual-phase materials with intelligent control of their reversible magnetic properties Call name: P 5.1 - Proiecte de Cercetare Exploratorie - Competiția 2023
PN-IV-P1-PCE-2023-1896 2025 - 2027

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website:

Abstract:

The main objective of the MAGIC-PRO project is to design, develop, and characterize a range of dual-phase magnetic materials that allow for the controlled switching between amorphous-like and nanocrystalline-like magnetic properties under the influence of an external stimulus, in order to achieve a wider range of tunability than current amorphous and nanocrystalline magnetic materials. The external stimulus would act on the magnetic anisotropy, changing the magnetic exchange length, which could therefore be either smaller or larger than the inter-grain distance. By accurately controlling the annealing of such materials, one could control the size and distribution of the nanocrystallites, which would in turn affect the magnetic properties.

The concept of reversible magnetic properties is novel and has never been explored before. Its achievement would be a significant breakthrough, as it would allow for the development of new and improved magnetic devices with significantly improved characteristics.

The associate objective of MAGIC-PRO is to exploit the potential applications of the novel dual-phase magnetic materials, grounded in their unique reversible magnetic properties. This includes, but is not limited to, the exploration and development of innovative mechanical stress sensing devices, magnetic field sensing devices, current sensors, or even sensing devices employing dual operating principles.

Design and development of novel photocromic materials based on spiropyrans for micropollutants removal Call name: P 5.1 - Proiecte de Cercetare Exploratorie - Competiția 2023
PN-IV-P1-PCE-2023-0303 2025 - 2027

Role in this project:

Coordinating institution: UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI

Project partners: UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI (RO)

Affiliation:

Project website:

Abstract:

Many biorefractory toxic compounds are present in water at low concentration levels (i.e., micro pollutants), which often makes their removal difficult and costly by conventional biological, physical and chemical methods. Post- or pre-treatment by photocatalysis is an economically feasible possibility to reduce recalcitrant wastewater compounds and achieve a water quality sufficient for reuse. Photochromic properties of ionic liquid functionalized spirogyras offer an alternative method to the removal of pollutants from waters. To our knowledge no spiropyran has been used for application in water treatment. Therefore, our goal in the project proposed hereby is to obtain new photoresponsive catalytic formulations based on spiropyrans and to assess their catalytic performances for the degradation processes of micropollutants.

Performance enhancement of direct methanol fuel cell (DMFC) by improving the catalytic activity and stability of the electrodes materials Call name: P 4 - Proiecte de cercetare exploratorie - PCE-2021
PN-III-P4-PCE-2021-1395 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/en/performance-enhancement-direct-methanol-fuel-cell-dmfc-improving-catalytic-activity-and-stability

Abstract:

Air pollution is currently the most important environmental risk to human health, and it is perceived as the second biggest environmental concern at national and international level. In this context, the replacement of the energy from fossil fuels with clean/green energy sources is imperative and the use of Direct Methanol Fuel Cell represents a viable solution to pollution issues, being one of the best candidates for the next-generation power source. The scope of the project proposal is to overcome two of the technical issues concerning the DMFC performance by: (i) developing a new preparation method of CoPt nanoparticles in order to increase the catalysts activity and decrease the platinum content and (ii) increasing the catalyst stability by exploiting the unique properties of CNTs. Within the framework of this project, a complex experimental study on the preparation, characterization (dimensional, morphological, structural and magnetic) and testing of new CoPt/CNTs nanocomposite materials will be accomplished, in order to choose the adequate catalysts in terms of nanoparticles diameter, morphology, structure and composition. By fulfilling the project proposal activities, we will contribute to the improvement of DMFC performances and stability and we will develop the experimental research work in the field of preparation of new catalysts based on CoPt /CNTs nanocomposite, focused on practical and immediate applications to renewable energy sources and catalyst industry.

Gold nanoparticles-based nanobiocomposites as artificial immunogens for human and animal immunization, respectively, against SARS-CoV-2 Call name: P 4 - Proiecte de cercetare exploratorie - PCE-2021
PN-III-P4-PCE-2021-1081 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/en/gold-nanoparticles-based-nanobiocomposites-artificial-immunogens-human-and-animal-immunization

Abstract:

The development of anti-SARS-CoV-2 vaccines is a current problem of humanity, the preparation of specific immunogens against such types of viruses becoming extremely important for the scientific, economic, technological, social, or cultural domains. Although vaccination is one of the most effective healthcare interventions, there are several social, clinical, and economic obstacles to vaccination, including a large number of people reluctant to new vaccines, the side effects of vaccination, the likelihood of varying vaccine effectiveness or poor efficacy in various populations, longevity of the immune protection and access to the vaccine for certain people.

Gold nanoparticles (AuNP) have aroused huge interest in vaccinology, due to their reliable surface functionalization, biocompatibility, size and shape customization, and optical properties. AuNP were exploitated in vaccines against bacterial infections, viral infections, cancer, parasite infections etc.

The goal of the project is to provide the vaccine and nutritional supplements industry with an immunogen against SARS-CoV-2 to be used as the major component in vaccines for COVID-19 prophylaxis. The novelty of the project regards the (a)Immunogen preparation; (b)Applications in vaccinology; (c)Solving the old problem of AuNP stability; (d)Solving the problem of ionic binding stability in aqueous solutions with high ionic strenght; (e)Preparation of immunizing nutritional supplements and vaccine industry and (f)Social level

Interstitial intermetallic materials of type α ″ -Fe16N2 for the new generation of rare-earth-free permanent magnets Call name: P 4 - Proiecte de cercetare exploratorie - PCE-2021
PN-III-P4-PCE-2021-0298 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/en/interstitial-intermetallic-materials-type-%CE%B1%E2%80%B3-fe16n2-new-generation-rare-earth-free-permanent-magnets

Abstract:

Permanent magnets (PMs) are critical components used in commercial and military applications. The most used PMs available today are based on Nd-Fe-B with additions of heavy rare earth Dy, Pr, Tb etc. Due to: (i) exponential increase in the request for PMs; (ii) the overall resource limitations, (iii) export restrictions imposed by China (the main supplier) on RE, and (iv) pollution resulting from the extraction and separation of RE, it is imperative necessary development of new RE-free magnetic materials. Consequently, in recent years several new candidate materials systems were investigated, and some have shown realistic potential for replacing RE PMs for some applications.

The project proposes to develop a type of PMs based on α″-Fe16N2 phase, able to fill in the gap between the most cost-effective but low performing hard ferrite magnet and the most expensive but high performing RE PMs.

The motivation of this choice start, from: (i) the fact that the component materials of the new magnet, iron and nitrogen are totally non-polluting, and (ii) α″-Fe16N2 phase promises theoretical a giant saturation magnetization.

The idea is to prepare iron nitride powder by high-pressure gas atomization with high volume ratio of α″-Fe16N2 phase and compaction of powders by spark plasma sintering technique. Due to experience and competence of involved team in and outcomes of research team in the hard magnetic materials domain, we believe that the project will be a successful.

Tunnel Magnetoresistance Sensor for Detection of Magnetic Nanoparticles Distributed in Human Tissue Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-2739 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/en/tunnel-magnetoresistance-sensor-detection-magnetic-nanoparticles-distributed-human-tissue

Abstract:

Due to their low fabrication cost, small size, low power consumption, and high sensitivity, magnetoresistive (MR) sensors are promising candidates for many biomedical applications. For such applications, a linear response of the MR sensors to the applied magnetic field is highly required. Although the most studied MR sensors are those based on the giant magnetoresistance (GMR) effect, those based on the tunnel magnetoresistance (TMR) effect have higher sensitivity, making them very attractive for medical applications. Anyway, for TMR sensors, some disadvantages such as a complicated technological process and low linear response to the application of a magnetic field have to be minimized.

Recently, studies have been conducted to detect magnetic particles (MPs) and evaluate their concentration in ferrofluids or to indirectly detect biomolecules or bacteria by detecting the magnetic field generated by MPs adhering to them. The development of a small size sensor with high sensitivity would be essential for magnetic hyperthermia, which currently suffers from the problem of localizing heat only at the affected site. As far as we know, there are no reports on scanning a surface with magnetic nanoparticles (MNPs) dispersed in it, detecting and determining of MNPs position using a TMR-based sensor. In this project, we aim to fabricate a simple model of a TMR-based sensor with small size and high sensitivity, capable of detecting MNPs in human tissue. After scanning a sample in which MNPs are dispersed, the sensor will provide information about the presence of particles, the quantification of their different concentrations, and their position in the sample.

To achieve the project goal, we will improve the TMR structure, microfabricate the sensor and magnetically characterize its performance. We will also build up an experimental setup for scanning and detection, and we will test the ability of the sensor to detect the MNPs from the tissue.

Permanent magnets with innovative design based on Mischmetal Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-1386 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/en/permanent-magnets-innovative-design-based-mischmetal-0

Abstract:

The discovery of Nd-Fe-B magnets in the 80’s was an important step in the history of permanent magnets (PMs) but also in the evolution of technology, in terms of the large number of applications generated. At that time, the Sm-Co based PMs had to be replaced because Co was a strategic and expensive material. However, in recent years both Nd and other rare earths (RE) such as Dy, Tb, which are part of Nd-Fe-B magnets have also become critical materials. In addition, the demand for PM has grown exponentially in recent years, mainly due to the accelerated development of areas such as green energy and robotics. Consequently, innovative design and development of new types of PMs with good performance, but without critical RE-has become an absolute priority.

Our project aims to develop and obtain a new type of nanocomposite PMs, based on a mixture of nanopowders (MMFeCoB / FeCo), able to present energy product between ferrite and NdFeB magnets and to fill the current gap between them. The motivation for replacing critical RE with Mischmetal (MM) is given by the fact that MM is a natural ore, consisting of a mixture of RE (La, Ce, Pr and Nd), and can be used directly without separating the elements. It is important to note that all RE are extracted from the associated ore and the process of separating and purifying is very expensive and polluting. The motivation for the development of exchange-coupled nanocomposite magnets is given by the fact that they theoretically have the highest maximum energy product.

Our idea is to obtain each component (soft and hard magnetic) in the form of nanopowders with optimal dimensions to ensure maximum exchange coupling and then turn them into PM with desired properties. Due to the experience and competence of the team involved as well as the previous results (we are able to produce nanopowders by cryo-milling) of the research team in the field of hard and soft magnetic materials, we believe that the project will be successful.

Magnetic particles and nanowires for non-invasive cancer cell destruction by controlled magnetomechanical actuation Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-2381 2021 - 2023

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/projects/en/MagneAct

Abstract:

This project addresses a topic of great scientific importance, namely the development of an anticancer therapy by using the magnetomechanical effect produced through the magnetic actuation of magnetic particles/nanowires in rotating magnetig field (RMF). The magnetomechanical actuation in a RMF leads mainly to the rotation of the magnetic particles/nanowires, by producing a torque whose magnitude depends on the magnetic field intensity, the magnetic moment and magnetic susceptibility of the particles/nanowires. The project includes all the steps for the preparation of desired magnetic particles (MPs) from Fe-ETM-Nb-B (ETM = Early Transition Metal = Cr, Ti, Mn) and Ni, Co, NiFe or CoFe nanowires (MNWs), their characterization, the investigation of the mechanisms governing their specific magnetic behavior, as well as the understanding of the interaction between MPs/MNWs and cells (cancer cells and normal cells). The process of destroying cancer cells will be performed by direct magnetomechanical effect or in association with other processes such as the use of STEM cells as vehicles for transport of MPs/MNWs or drug-coated MPs/MNWs and controlled release of antitumoral drugs bound to particles.

Magnetic Domain Wall Structures in Cylindrical Rapidly Quenched Amorphous Glass-Coated Nanowires – Applications in Magnetic Logic Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-1856 2021 - 2023

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation:

Project website: http://www.phys-iasi.ro/projects/en/MaDWallS

Abstract:

We aim to understand at a phenomenological/theoretical level and to experimentally emphasize the intimate structures of magnetic domain walls forming in rapidly quenched cylindrical amorphous glass-coated nanowires. Investigations will also focus on changes in such domain wall structures with nanowire dimensions and alloy compositions. To stress the practical importance of knowing the exact types of domain wall structures in rapidly quenched cylindrical amorphous nanowires, we will develop a laboratory demonstrator of an optimized domain wall conduit based on such cylindrical nanomaterial. The optimized domain wall conduit will be used to demonstrate and validate controlled operations with actual domain walls, e.g. generation/nucleation, propagation, interaction with other domain walls (collisions), stopping/trapping, as well as energy barrier crossings.

The practical aspects of moving an existing domain wall along a nanowire (for magnetic logic applications) are closely related to the magnetization distribution within that wall, allowing, for instance, the use of electrical currents to propagate the domain wall. We will correlate the results of experimental investigations (Lorentz transmission electron microscopy, volume and surface magnetic hysteresis, ferromagnetic resonance) with those of theoretical ones (analytical and micromagnetic modeling) in order to accurately describe the domain wall structures that can form in rapidly quenched cylindrical amorphous nanowires.

Intelligent detector for radioactive particles spread over large geographical areas Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4225 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL DE CERCETARE-DEZVOLTARE PENTRU APICULTURA SA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.mwe.ro/

Abstract:

The intelligent detector for radioactive particles spread over large geographical areas refers to a method and a system for real-time detection of the presence of radioactive particles in the environment, interconnecting the universe of bees with self-organizing capabilities as a carrier and transporter of radioactive particles with the universe of computers which processes information on their presence and nature and sends alert messages in case of radioactive contamination. It contains a network of ionizing radiation sensors provided with amplification modules, a bee meter module used to obtain information about their flight and avoidance of false messages in case of increased mortality, a local computer based on several central units of parallel data processing ensuring the high speed of processing the information provided by the sensors, a weather micro-station module used to estimate the direction of movement of radioactive particles, a GPS module used to obtain information on the geographical location of the detector, a GSM module used to transmit alert messages in case of radioactive danger, a photovoltaic power supply module used to ensure energy autonomy.

Nanosized Cylindrical Magnetic Conduits for Ultra-Fast Domain Wall Logic Operations Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-0586 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.phys-iasi.ro/en/projects/en/NanoCyliCon

Abstract:

The aim of this project is to develop optimized ultrathin amorphous and nanocrystalline magnetic submicron wires and nanowires to be employed as novel NanoCyliCon domain wall conduits with cylindrical symmetry, in which we will demonstrate controlled operations with ultra-fast domain walls for magnetic logic applications. The controlled domain wall operations will be: domain wall formation (i.e., nucleation), domain wall propagation (displacement), domain wall trapping (with various types of energy barriers), energy barrier crossing and domain wall interactions (collisions). Such phenomena are essential for future magnetic domain wall logic gates. The main novelty is the use of these newly developed ultrathin magnetic wires (TRL 2) to achieve such a precursor or master magnetic logic application like the optimized NanoCyliCon domain wall conduit laboratory demonstrator (TRL 3). A specific set-up will be developed within the project in order to investigate, test and control the domain wall operations in optimized amorphous and nanocrystalline submicron wires and nanowires, and to show, demonstrate, enhance and validate their repeatability limits. The final result of the project will be a domain wall conduit with superior symmetry and dynamic characteristics in which an enhanced control of ultra-fast domain wall operations will be demonstrated and validated, along with the associated know-how.

Optimization of Fe-ETM-Nb-B (ETM = Early Transition Metal = Cr, Ti, Mn) magnetic particles production technologies for cancer therapy Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3442 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.phys-iasi.ro/en/projects/en/optimag

Abstract:

Cancer is responsible for about 25-30% of deaths in developed countries, being the second cause of death after cardiovascular diseases. Systemic therapies, including chemotherapy and radiotherapy have long been considered to be the main way of treatment, but there is a tendency to reduce the negative effects of these methods by applying the treatment to a restricted area, where the tumor is located. Magnetic particles (MPs) have been lately used in biomedicine for magnetic separation, as magnetic carriers for drug delivery, as thermoseeds in magnetic hyperthermia (HT) and, more recently, for their ability to induce apoptosis by mechanical forces. Our MPs of micro/nanometric dimensions from the Fe-ETM-Nb-B system are part of a highly important field of research, developed recently at INCDFT-IFT Iasi. The dimensional and magnetic characteristics of these materials have been highlighted in IFT Iasi and attested through numerous publications. These MPs led to a series of important medical applications especially related to cancer therapy, applications that have been tested by IFT Iasi and confirmed by numerous scientific communications and publications. These particles were obtained at laboratory level, regardless the difficulties related to the afferent technological elements. IFT has applied and obtained a patent for these materials, in Romania and USA, the action being in progress in other countries. The main objective of this project is the integration of the technological steps involved in the production of micro- and nanometric particles based on Fe-ETM -Nb-B in order to achieve a functional assembly of such MPs with characteristics required for medical applications such as hyperthermia, magneto-mechanic effect, drug delivery and coupling with STEM cells for the common action of transport in the body to malignancies as well as validation at the laboratory level of each technological stage and the technology as a whole.

Smart composite system with self-controlled configuration developed from shape memory/ amorphous magnetic materials in elastomeric matrices Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4138 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); R&D CONSULTANTA SI SERVICII S.R.L. (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.phys-iasi.ro/en/projects/en/smamem

Abstract:

The present project aims to develop a novel smart composite system, constituted of shape memory alloy (SMA)/ amorphous magnetic materials embedded into elastomeric matrices (SMA-AM/ E) with self-controlled configuration and extended functionality, dedicated to the operation, detection and monitoring of fluid volume, temperature and transition parameters, such as recipients with controlled volume, hydraulic pumps, multifunctional pipes for complex fluid transportation or even stents. Thermoelastic SMAs, such as Ni-Ti-Cu(Nb, Ta) that are nonmagnetic and martensitic at room temperature (RT), will be designed and produced by the Company „R & D Consultanță și Servicii” (P3), under the form of cylindrical ingots. The “ Gheorghe Asachi” Technical University of Iasi (P1) will homogenize the ingots that will be cut, hot rolled, heat treated and thermomechanically trained into active elements, which will be attached firstly into 2D flexible modules comprising 3 to 6 elements and finally into 3D systems. The National Institute of Research and Development for Technical Physics Iasi (CO) will produce, process and characterize the amorphous magnetic microwires, melt spun from Co-based ultra-soft magnetic alloys. CO will study the integration of amorphous microwires into the host composite consisting of a SMA skeleton incorporated into flexible elastomers. “Petru Poni” Institute of Macromolecular Chemistry (P2) will synthesize and characterize the elastomeric matrix based on polysiloxanes, which needs to be flexible and temperature-resistant. CO, assisted by P1 and P2 will test the functionality of several variants of experimental smart systems with different number of 2D modules and different initial configurations of the modules comprising 3-6 active elements

Novel Permanent Magnets based on Ce2(FeCo)14B/Fe65Co35 Core Shell Nanoparticles Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-2054 2020 - 2022

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.phys-iasi.ro/en/projects/en/nanomagshell

Abstract:

In the last two decades, permanent magnets (PMs) have become vital components used in advanced electronics systems, military applications, robotics and emerging green energy technologies like the hybrid electric vehicle (HEV) and wind turbines. The strongest and most used PMs available today are based on Nd-Fe-B type alloys with additions of heavy rare earth Dy, Pr, Tb etc. However, due to: (i) exponential increase in the request for PMs, (especially in the green energy and robotics field); (ii) the overall resource limitations and (iii) export restrictions imposed by China (the main supplier) on rare earths, these heavy rare earths becomes materials of risk. Consequently, there is a strong need to find and produce new permanent magnets without heavy rare earths, but with functional performance as good as possible. The our project proposes to develop and to obtain a new type of permanent magnets based on core-shell-type (CeFeCoB/FeCo) nanopowders, PMs able to develop magnetic performance in order to fill the gap between energy product of ferrites and NdFeB magnets based on critical rare earths.

The motivation of this choice start, from: (i) the fact that (Ce), is more abundant, and the quantitatively is 4 times more than Nd and Pr taken together, and (ii) our preliminary results where we obtained CeFeCoB ribbons with our preliminary results where we manage to obtained CeFeCoB ribbons with remarkable magnetic properties. Also, we are able to produce nanopowders by cryo-milling technique.

The idea is to envelop Ce-FeCo-B as individual nanoparticles with FeCo soft phase, in order to ensure maximum exchange coupling and after that to turn them into PMs with desired properties by spark plasma sintering technique. Due to experience and competence of involved team in and outcomes of research team in the hard and soft magnetic materials domain, we believe that the project will be a successful.

ANTITUMORAL THERANOSTIC PLATFORMS BASED ON CARBON DOTS AND POLYMER MATRICES Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0083 2018 - 2021

Role in this project:

Coordinating institution: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI

Project partners: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); INSTITUTUL REGIONAL DE ONCOLOGIE IAŞI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.cercetare.icpm.tuiasi.ro/proiecte/TERADOT/

Abstract:

The TERADOT consortium will implement this project with the aim of reaching its strategic objective: the consolidation of the consortium scientific and technical competencies (in particular those of the P3 partner with relaunch potential) in the field of econanotechnologies and advanced materials by supporting / developing the existing research competences and the transferability of its research results. The TERADOT Consortium is an alliance that will devote its efforts to capitalize the potential of nanotechnologies by creating new teranostic platforms based on Carbon Dots (CDs) in order to radically change the proceedings to diagnose and treat cancer. Building on the significant preliminary results obtained by the project's members, the consortium represents a systematized initiative, comprising four public sector institutions, having the potential to be expanded with private-sector entities, designed to accelerate the application of these new concepts of cancer diagnosis / treatment. The project consists of three distinct subprojects aiming at: 1. Obtaining and testing of some CDs-type nanostructures starting from imidic precursors, suitable as teranostic investigation / anti-tumor treatment platforms; 2. Obtaining and testing of polymeric biocomposites containing imidic CDs, suitable as teranostic investigation / anti-tumor treatment platforms; and 3. Developing a pilot-scale process for synthesizing CD-type nanosciences for medical applications. The TERADOT project proposes to achieve these objectives by accomplishing several specific output indicators, of which the most important are: the employment of eight young researchers, obtaining 4 new products, 1 new technology for CDs preparation, minimum 8 articles in high impact journals, 5 patent requests (4 national and 1 international) which will further facilitate the collaboration with economic entities as potential beneficiaries.

Technologic paradigms in synthesis and characterization of variable dimensionality systems Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0152 2018 - 2021

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA

Project partners: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEHNOLOGII CRIOGENICE SI IZOTOPICE - I.C.S.I. RAMNICU VALCEA (RO); UNIVERSITATEA DE VEST TIMISOARA (RO); INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://infim.ro/project/vardimtech/, http://infim.ro/project/vardimtech-en

Abstract:

Last decades brought a considerable development of technologies based on ordered systems. Starting with semiconductor physics and photovoltaics, technologies soon evolved towards the utilisation on large scale of thin films and of surface / interface properties. Example go nowadays from data storage and readout (electrostatic or magnetic memories, giant magnetoresistance) to catalysis, gas sensors or photocatalysis (surface phenomena), and towards interfaces with biological matter (biosensors, templates for tissue reconstruction, interfaces between biological electrical signals and microelectronics). In Romania, crystal growth is performed since half a century; nevertheless, during the last years these activities fade out and need to be seriously reinforced, especially with the advent of new laser and detector technologies required by the Extreme Light Infrastructure facilities. Also, surface science started to be developped seriously only during the last decade, together with techniques involving self-organized nanoparticles, nanoparticle production etc. The main goal of this Project is to gather the relevant experience from the five partners, namely the experience in crystal growth from the University of Timișoara, with the surface science, nanoparticle and nanowire technologies developped by NI of Materials Physics, the cryogenic and ultrahigh vacuum techniques provided by the NI for Cryogenic and Isotopic Technologie, and the experience in ordered 2D systems (graphene and the like) owned by the NI for Microtechnologies (IMT). This common agenda will result in a coherent fostering of technologies relying on ordered systems of variable dimensionalities: 0D i.e. clusters or nanoparticles, including quantum dots; 1D i.e. free and supported nanowires and nanofibers; 2D: surfaces, interfaces and graphene-like systems; and 3D crystals of actual technological interest, together with setting up new ultrahigh vacuum, surface science and electron spectroscopy techniques.

New advanced nanocomposites. Technological developments and applications Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0871 2018 - 2021

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA

Project partners: INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA DE VEST TIMISOARA (RO); ACADEMIA ROMANA FILIALA TIMISOARA (RO); UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO); UNIVERSITATEA "DUNAREA DE JOS" (RO); UNIVERSITATEA TRANSILVANIA BRASOV (RO); Ministerul Apararii Nationale prin Centrul de Cercetare Stiintifica pentru Aparare CBRN si Ecologie (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://infim.ro/project/kuncser_noi_directii_de_dezvoltare_tehnologica_si_utilizare_nanocompozite_avansate_47pccdi_2018

Abstract:

The development of complex nanocomposite materials consisting of different matrices (polymer-like, oxides, intermetallics, liquids) functionalized by different nasnostructured additions (carbon allotropes, magnetic nanoparticles with different organizations, nanostructured semiconductors, etc.) is the aim of this project. The unique combinations of interacting nanophases offeres to the hybrid nanocomposite material new or enhanced proprieties of high interest for applications. In this context, according to the previous experience of the involved teams, the complex project (formed by 4 component projects) is focused on the development of new optimized nanocomposite systems to be included in experimental demonstrators or final products to be transferred to economical companies. The project will contribute both to an increased scientific visibility of the partners as well as to enhancing the institutional performances by the development of new technical and scientific capacities.

Near-Lossless Magnetic Domain Wall Nano-Conduits for Spintronic Applications Call name: P 4 - Proiecte de Cercetare Exploratorie
PN-III-P4-ID-PCE-2016-0358 2017 - 2019

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT IASI (RO)

Project website: http://www.phys-iasi.ro/en/projects/en/noloss

Abstract:

The aim of this project is to explore the development of near-lossless domain wall nano-conduits using cylindrical magnetic nanowires and submicron wires in order to reach record-breaking domain wall velocities and mobilities for domain wall logic applications. This envisages both an understanding of the role of wire cross section geometry (circular vs. rectangular in the case of the state-of-the-art planar nanowires) in domain wall mobility and of the wires’ magnetic domain structure on its domain wall velocity and mobility. Why is this important? Since typical magnetic wires prepared by rapid solidification usually exhibit a core-shell type magnetic structure, and, depending on the magnetization of the shell, it may enhance or obstruct the propagation of the domain wall within the core. On the other hand, going to sufficiently small values with the wire diameter may result in a single-domain magnetic structure, which could drastically alter the domain wall mobility and velocity. This also depends on the overall magnetic anisotropy within the wire. Therefore, the structural characteristics of the wires are also an essential factor (e.g., amorphous vs. nanocrystalline). All these aspects have to be carefully and comprehensively investigated in order to control and diminish any potential losses and enhance the domain wall propagation characteristics (mobility, velocity) as much as possible for increased device speed in magnetic logic applications.

The use of the near-lossless cylindrical nanowires/submicron wires as domain wall conduits for magnetic logic applications would result in a completely novel and different way of processing the information, characterized by enhanced data speeds, along with reduced power consumption. Magnetic logic has even more advantages over conventional electronic logic, given that it uses no transistors, and therefore, it exhibits very little heating caused by data switching.

Smart Microsensors Array for Non-Intrusive Flow Rate Measurements Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0471 2014 - 2017

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); GRADIENT S.R.L. (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://www.phys-iasi.ro/en/projects/ro/smartflow

Abstract:

The aim of this project is to develop the prototype of the SmartFlow system, i.e. an array of intelligent and autonomous microsensors for the non-intrusive measurement of the volume flow rate of liquids through a network of pipes made of various materials. Each microsensor from the array will possess bi-directional wireless communication capabilities, so that the array will form a wireless sensor network (WSN) with the possibility of controlling the sensor activity (enable or disable each individual microsensor). The microsensors will possess enhanced autonomy through the inclusion of an energy harvesting module (EHM), which will significantly prolong their operating time. The vibrating element, which will harvest the energy from the vibrations, will be the same special magnetic material which will be employed as the vibration sensing element within the individual microsensors. The operating principle of each non-intrusive flow rate microsensor within the array will be the change in the magneto-impedance (MI) response of a novel magnetic material due to the vibrations in the pipe wall induced by the flowing liquid. A central monitoring station (CMS) will collect, process and correlate the data from all the microsensors within the SmartFlow system. The CMS software will control the entire system and will be focused on usability in terms of end-user control. The developed SmartFlow system is intended for applications such as monitoring the flow rates in civilian water supply systems, in wastewater management systems, in the nuclear industry and in the geothermal industry, but it is also suitable for food industry applications. It will also represent a viable and low-cost alternative for the clamp-on ultrasonic flow measurement of fuels such as diesel and petrol. An associated goal is to demonstrate the operation of the SmartFlow system in a specific application. The end product of the project will consist in the prototype of the fully functional SmartFlow system.

Magnetoelectric composites with emergent properties for wireless and sensing applications Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1119 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI

Project partners: UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI (RO); GRADIENT S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://stoner.phys.uaic.ro/projects/national-projects/213-mecomap-pnii-pt-ro.html

Abstract:

The aim of the present multidisciplinary project is to design by modeling&simulation, produce by innovative synthesis methods and various sintering strategies, to investigate the physico-chemical properties at various length scales of a few types of magnetoelectric composites with emergent properties in order to integrate them at industrial scale in a few types of new applications. Two types of devices based on magnetoelectric composites will be produced: (i) miniaturised magnetoelectric tunable reconfigurable antennas based on particulate ceramic composites; (ii) new types of sensors / transducers / actuators / harvesters based on layered magnetoelectric composites. The project will contribute to increase the consortium capacity to approach top research subjects in the field of smart multifunctional materials with high applicative potential. In terms of material science aspects, an important contribution will be given by a complex physico-chemical experimental – modeling approach for understanding the relationship between composition, micro/nanostructural parameters and functional properties of the magnetoelectric composites with different degrees of phase connectivity. The composition, phase interconnectivity and microstructures will be optimised and the best composite structures will be selected for the proposed applications. By considering the dielectric, ferro/piezoelectric and magnetoelectric properties of the produced composites, new magnetoelectric devices will be designed, realised, tested and optimised and the best solutions in terms of both technical parameters and cost efficiency will be implemented as prototypes by the industrial partner. The new devices are expected to contribute to the increase of the company performances by extending its production capacities, by extending the number of high specialised employees and the number of its beneficiaries. The overall scientific goal is to improve the knowledge in the field of multifunctional magnetoelectric composite structures at different levels (macroscopic, mesoscopic and at nanoscale) in order to generate properties beyond the present ones and to integrate them into new magnetoelectric devices with superior characteristics and low cost.

Spatial electromagnetic shields based on differentiated functionalization with nano/micro-particles Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-1115 2014 - 2017

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); ART LIMITED SRL (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://www.phys-iasi.ro/en/projects/ro/difshield

Abstract:

The project proposes the development of a new concept of composite fabrics to be used for manufacturing electromagnetic shields with superior shielding effectiveness compared with the current structures. Its thematic is correlated with 7th Area: Materials, processes and innovative products, Research direction 7.1. Advanced materials. Research topic 7.1.8. Advanced materials for niche sectors of the economy.

The composite shield will be made as a spatial textile structure whose functionalized fibres’ arrangement, resulted from theoretical analysis, behavioural simulations and experimental optimizations, will maximize the electromagnetic shielding effect through reflection, absorption and multiple reflections of the incident radiation. In parallel, a new functionalization technology, representing a customization of dielectrophoresis and consisting in replacing one of the active electrodes with the fabric subject to functionalization, will be developed.

Currently, an increased shielding effectiveness of composite shields is achieved at the cost of losing their main advantages, namely: high flexibility, reduced weight and low manufacturing costs. In this context, the project proposes the development of a new type of multilayer textile shield, implementable in a single technological process of spatial knitting, which preserves the advantages of composite shields and exhibits a shielding effectiveness comparable to homogeneous metal shields. This will be achieved by the specific orthogonal arrangement of fibres, and by the differentiated functionalization of the layers with ferro or non-ferromagnetic micro/nano-particles, addressing individually the reflection and absorption effects.

The proposal’s claims on originality refer to:

1. The complex structure of the proposed shield, a three-layer structure, optimized in terms of geometry and active materials used for the functionalization of each layer.

2. A new differentiated functionalization technological method, indispensable for achieving a low-cost shield structure, but whose general character makes it applicable to other categories of materials.

The consortium consists of three partners, whose complementarity ensures the development and testing of DifShield shield and prepares its market launch, by developing plans for results exploitation and technological transfer.

When establishing the consortium’s structure, the complementarity between the partners was taken into account, as being a compulsory condition for the achievement of the project’s central objective, the development of the shield with functionalized spatial structure with micro and nano-particles. Thus, it was considered the presence of an institution which can produce micro and nano-particles, with the possibility of optimising their shielding properties, (INCDFT), an institution specialized in electromagnetic field simulation and measurement of reflected and absorbed electromagnetic radiation (TUIASI) and an institution capable to implement the spatial structure with composite yarns, in the form of independent layers (ART Limited).

The research infrastructure provided by the partners involved in the project include a full range of equipments designed for micro and nano-particles production, their characterization, knitting composite spatial structures, their functionalization, functionalization homogeneity verification and shielding effectiveness measurements. This infrastructure together with the experimental facilities owned by the partners guarantee that all the projected activities can be carried out in the budgeted time, at top quality level.

COMPLEX LANDSLIDE MONITORING SYSTEM USING TRANSDUCERS BASED ON NEW MATERIALS AND TECHNOLOGIES Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-0975 2012 - 2016

Role in this project:

Coordinating institution: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI

Project partners: UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE PENTRU FIZICA MATERIALELOR BUCURESTI RA (RO); UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI (RO); QUARTZ MATRIX SRL (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://www.landslide.tuiasi.ro

Abstract:

The project objective is conceiving, design, realization and testing of a complete and complex system devoted to continuously monitoring the displacement under three axes of the geomorfological structures and of other specific parameters in order to detect and monitor landslides by using smart sensors based on special micro and nanostructured materials and advanced information processing techniques. The system is able to automatically acquire data on the filed, locally processing information and storing and remotely data transmitting by means of a wireless sensor communication network to a central server. The system comprises three parts: i) instrumentation part, ii) communication part and iii) data processing and user interface part. The instrumentation part consists of a complex set of new transducers devoted to measure very small spatial soil displacements, pore water pressure, conductivity and temperature at different levels under ground. The communication part is a wireless sensor network working under protocols specially designed for this application. The third part is the database continuously updated available for all users by means of a web interface. The project will have a coordinator and 4 partners from which one is a medium enterprise. The project activities are divided into four phases: the first phase devoted to building the instrumentation part, the second, to laboratory testing and calibration of all sensing devices, the third to system assembly and to realization and testing of wireless sensor network and the fourth to testing the monitoring system on the field working under real conditions. There are previewed a series of concrete deliverables materialized on four new types of sensors, the complex smart transducer, the sensor network, the assembly system ready to be implemented on the field and a database contained date collected on a high natural hazard risk area and a user friendly interface on which people may watch on the web the phenomenon.

Low Curie Temperature Magnetic Particles for Hyperthermia Applications Call name: Joint Applied Research Projects - PCCA-2011 call, Type 1
PN-II-PT-PCCA-2011-3.1-1406 2012 - 2016

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "GR. TH. POPA" (RO); UNIVERSITATEA "ALEXANDRU IOAN CUZA" IASI (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://www.phys-iasi.ro/en/projects/ro/hyperthermia

Abstract:

The project entitled “Low Curie Temperature Magnetic Particles for Hyperthermia Applications” is a multidisciplinary one and will be realized by a consortium comprising the National Institute of Research and Development for Technical Physics Iasi as Coordinator (CO), “Gr.T. Popa” University of Medicine and Pharmacy Iasi as partner P1 and Al. I. Cuza University Iasi as partner P2.

The aim of the project is the preparation of a new type of magnetic micro and nanometer- sized particles with low Curie temperature, which can be controlled in the 40-60ºC range, for hyperthermia applications. The presence of such particles around a tumor permit to heat it up to a self regulated temperature equal to the Curie temperature of particles (42, 43 or 44ºC), with a precision of 0.5ºC leading to the cancer tumor regression. The implementation of the proposed project is based on new results announced by NIRDTP on the preparation of rapidly quenched magnetic ribbons with compositions based on Fe, Cr, Nb, and B which present low Curie temperature controllable through the composition. During the project development, micro- and nanoparticles will be prepared using high-energy grinding and by arc discharge. The increase and self-control in the temperature of the particles in an applied high frequency electromagnetic field as well as the flow of the particles in simulated blood vessels conditions will be investigated using experimental set-ups constructed in the frame of the project. Tests on the particles biocompatibility and investigation of the effect of hyperthermia on tumors evolution will be performed “in vivo”. A phenomenological model for the magnetic behavior of particles will be elaborated. The modeling and simulations for the particles will be used to predict the temperature evolution in the tumor location. The novel materials proposed in this project will bring a timely and valuable contribution to the use of hyperthermia in cancer therapy.

Interdisciplinary research on multifunctional hybrid particles for bio-requirements Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-0428 2012 - 2016

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI"

Project partners: INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "GR. TH. POPA" (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO); REZISTOTERM S.R.L. (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA TEHNICA-IFT RA (RO)

Project website: http://www.icmpp.ro/projects.html

Abstract:

The project with multi-disciplinary character is focused on analysis and solving from the physical, chemical and biochemical viewpoint the design and technology of novel systems, based on antioxidants-loaded core-shell magnetic nanocomposites deposited onto the stent surface. Novel formulation methods based on the use of biocompatible polymers will be developed and applied to create a family of magnetic nanoparticles (MNPs) further characterized as a platform for magnetically guided delivery of therapeutics. The selected polymers will undergo physical (forming of interpolymer complexes by physical interactions) and chemical (functionalization, derivatization, crosslinking, reactive mixing) modifications in order to obtain stable multifunctional nanosystems. The key features of the new target delivery systems will be investigated, including in vitro bioactive compounds activity, capacity to protect the antioxidants from proteolysis, as well as the capacity of the magnetic guidance and retrieval. The project includes aspects like toxicology, biocompatibility of the nanodevices, and also efficacy and biodistribution of the system.

One of the most innovative aspects of this proposal is the use of functionalized MNPs with antioxidative biomolecules deposited onto the stent surface to realize a drug-eluting-stent type for bio-requirements. The new stent device will functioning as a delivery platform. At the same time, the prepared MNPs will represent a particularly appropriate tool based on their ability to be simultaneously functionalized and guided by an external magnetic field; the presence of the antioxidative biomolecules would be an additional benefit. To conclude, the purpose of the multi-disciplinary project is to realize target delivery systems based on hybrid bio-nano-composites with improved magnetic performance of NPs and maximized therapeutic potential of the drug eluting/retrieval stents by the loaded antioxidative biomolecules layered on the stent surface

DOPING AND SIZE EFFECTS ON THE MAGNETIC, STRUCTURAL AND MORPHOLOGICAL PROPERTIES AND SPIN DYNAMICS IN MICRO AND NANOSTRUCTURED FERROMAGNETIC OXIDES. Call name: Complex Exploratory Research Projects - PCCE-2008 call
PN-II-ID-PCCE-2008-0106 2010 - 2013

Role in this project:

Coordinating institution: Universitatea Tehnica din Cluj Napoca

Project partners: Universitatea Tehnica din Cluj Napoca (RO); Institutul National de Cercetare Dezvoltare pentru Tehnologii Izotopice si Moleculare-INCDTIM-Cluj Napoca (RO); Institutul National de Cercetare Dezvoltare pentru Fizica Tehnica-INCDFT-Iasi (RO); Institutul National pentru Fizica Materialelor-INCDFM-Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU METALE NEFEROASE SI RARE (RO); Universitatea Politehnica din Bucuresti (RO)

Affiliation: Institutul National de Cercetare Dezvoltare pentru Fizica Tehnica-INCDFT-Iasi (RO)

Project website: http://c4s.utcluj.ro/Current%20projects%20-PNII.html

Abstract:

Diluted magnetic oxides (DMO) are expected to play an important role in interdisciplinary materials science and future electronics because charge and spin degree of freedom coexist into single material. The control of the high temperature ferromagnetism and of the spin and charge transport in DMO micro- and nanostructures represent a necessary condition for the achievement and miniaturization of spintronic devices which could operate at and above the ambient temperature. The project involves a competitive and complementary partnership between 2 Technical Universities and 4 National R&D Institutes and has the main goal to obtain top research results based on the experimental and theoretical researches which will be performed on micro- and nanostructured semiconducting ferromagnetic oxide systems synthesized by innovating methods. By means of that, it will be answered to the still controversial problems in the fundamental research referring to the effects induced by the low dimensionality, magnetic ions doping degree and by the synthesis methods on the propitious characteristics necessarily to get the high temperature ferromagnetism in II-VI oxide semiconductors.

Surface and Interface Science: Physics, chemistry, biology, applications. Call name: Complex Exploratory Research Projects - PCCE-2008 call
PN-II-ID-PCCE-2008-0076 2010 - 2013

Role in this project:

Coordinating institution: INSATITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA MATERIALELOR

Project partners: INSATITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA MATERIALELOR (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU INGINERIE ELECTRICA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE CAROL DAVILA DIN BUCURESTI (RO); UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA TEHNICA DIN IASI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE DIN CLUJ-NAPOCA (RO); UNIVERSITATEA BABES-BOLYAI DIN CLUJ-NAPOCA (RO); ACADEMIA ROMANA FILIALA TIMISOARA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE VICTOR BABES TIMISOARA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA TEHNICA DIN IASI (RO)

Project website: http://www.infim.ro/projects/siinta-suprafetelor-si-interfetelor-fizica-chimie-biologie-aplicatii

Abstract:

This project intends to provide a financial background for developing the community of Surface Science in Romania. Thematics from physics and chemistry of surfaces will be tackled together with applications of surface science in biology and in technology; also new standards will be proposed for consistent data interpretation. The Project clusterizes the most important Romanian teams with preoccupations in surface science, namely all X-ray photoelectron spectroscopy teams with most of the community of thin film deposition, cluster and nanoparticle physics, surface reactivity, surface chemistry and photochemistry, multilayer physics and applications, magnetic fluids, functionalization of surfaces, cell attachment, studies of cellular membrane. The research teams belong to highly prominent Universities and Research Institutes from practically all geographical areas of the country. The Consortium disposes of infrastructure exceeding 10 million euros, of more than one hundreed highly qualified scientists which have generated during the past years more than 3 % of the national scientific visibility. The research will concentrate into four main areas: (i) magnetic properties of surfaces and low-dimensional systems; (ii) electrical properties of surfaces and heterostructures; (iii) surface chemistry; (iv) application of surface science in functionalized systems and in biology, together with (v) an area concentrating on standardization in X-ray photoelectron spectroscopy, Auger electron spectroscopy and related techniques. Each area is divided into several thematics; each thematic has at least one in-charge scientist. This Project will foster the surface science community in Romania and will contribute strongly to the development of high-technological industrial preoccupation in all geographical areas concerned. Several cutting-edge applications are also foreseen by pursuing the fundamental research proposed.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator	Download (63.38 kb) 08/04/2015
List of research grants as partner team leader	Download (60.27 kb) 08/04/2015
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects	Download (93.12 kb) 22/04/2016