BrainMap

Mr. Mihai GÎRȚU

Dr.

Professor - UNIVERSITATEA OVIDIUS

Researcher | Teaching staff | Scientific reviewer | Manager

Web of Science ResearcherID: B-4574-2008

Expertise & keywords

INNOVATIVE NANOSTRUCTURED NUTRACEUTICALS WITH SYNERGISTIC BIOACTIVITIES FOR HEPATO-DIGESTIVE PROTECTION Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-1788 2022 - 2024

Role in this project:

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners: UNIVERSITATEA OVIDIUS (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); UNIVERSITATEA NAŢIONALĂ DE ŞTIINŢĂ ŞI TEHNOLOGIE POLITEHNICA BUCUREŞTI (RO); STATIUNEA DE CERCETARE DEZVOLTARE PENTRU VITICULTURA SI VINIFICATIE MURFATLAR (RO)

Affiliation:

Project website: https://univovidius.wixsite.com/nutrasinpro

Abstract:

The project entitled “INNOVATIVE NANOSTRUCTURED NUTRACEUTICALS WITH SYNERGISTIC BIOACTIVITIES FOR HEPATO-DIGESTIVE PROTECTION (NUTRASINPRO)” falls in the priority research domain of the present competition call, Bioeconomy, Subdomain Biotechnology. The general objective is obtaining of controlled nanostructure delivery systems based on natural raw materials mixtures as fluid fruits extracts of bitter cherry (Prunus avium var. sylvestris L.) and blue honeysuckle (Lonicera caerulea L.), grape pomace (Vitis vinifera L.) as by-product of grape winemaking encapsulated into a hybrid silica–barley germs mass (Hordeum vulgare as prebiotics) nanomatrix enriched with Lactobacillus sp. strains as probiotic. The main objectives of the project are design of new nutraceuticals formula obtained from high functional food-grade bioactive agents (anthocyanins, carotenoids, polyphenols, flavonols, flavones, vitamins, lipids, oligominerals) present in vegetal extracts encapsulated within a hybrid silica matrix-barley germs biomass nanostructure in different ratio; obtaining an innovative series of nutraceuticals delivery nanosystems exhibiting synbiotic action of prebiotics–probiotics constituents with synergistic therapeutically action; controlled delivery systems by nanoscale targeted level, with synergistic bioactivities, antimicrobial, antioxidant, anti-inflammatory and hepato-digestive protection and development of new technologies to obtain nutraceuticals nano-formulations conditioned as orodispersible tablets, controlled release tablets and lyophilized powder for oral use, protected by property rights. The envisaged end products: 1. Patenting the optimal variant nanostructured nutraceutical formulas of the new nanostructured target delivery system and issued in improving oral bioavailability for all ages group; 2. Technological process development for widely implementation of nanostructured nutraceutical formulations, used without risk on human, animal or environment health.

Cross-Border Maritime Spatial Plan for the Black Sea - Romania and Bulgaria Call name:
EASME/EMFF/2014/1.2.1.5/2/SI2.707672 MSP LOT 1 Black Sea -

Role in this project: Partner team leader

Coordinating institution: MINISTERUL DEZVOLTĂRII REGIONALE SI ADMINISTRATIEI PUBLICE

Project partners:

Affiliation:

Project website: http://www.marsplan.ro/en/

Abstract:

The main objective of the project is to support the implementation of the EU Directive for Maritime

Spatial Planning in the Black Sea Basin, starting with its Member States, Romania and Bulgaria. By

creating a MSP institutional framework for Romania-Bulgaria cross-border cooperation, the project

will bring together the major stakeholders , starting with the Mangalia-Shabla region.

Funded by the EC (EASME) through EMFF. Consortium of nine partners from Romania and Bulgaria.

Methodological advances and theoretical experiments on the bonding regime and properties design. From atoms to supra-molecules. Call name: Exploratory Research Projects - PCE-2012 call
PN-II-ID-PCE-2012-4-0633 2013 - 2016

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU

Project partners: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Affiliation: INSTITUTUL DE CHIMIE FIZICA - ILIE MURGULESCU (RO)

Project website: http://www.icf.ro/pr_2013/PN-II-ID-PCE-2012-4-0633/FC-PCE-2013.html

Abstract:

The project is devoted to original theoretical and methodological advances that imply a non-routine approach of quantum and computational chemistry. Selecting several important problems we put the accent on conceptual innovation rather than on the exhaustive and quantitative exploration. A first series of objectives concerns the treatment of lanthanide-based endohedral fullerenes by multiconfigurational procedures and subsequent spin-orbit treatments, using original strategies, by assembling a starting wave function from separate fragments. Our treatments enable the realistic description of many effects, paving the way to innovative predictions such as spintronics with lanthanide endohedral fullerenes. Other objectives concern non-metal endohedral fullerene, using a new method to extract host-guest interacting potentials by equating the vibration shifts of the encapsulating host. The same procedure is adapted to systems with tubular topology of the host. The resulting models have relevance for understanding dynamic effects in supramolecular assemblies. Finally, we focus on planar polyaromatic carbon materials using model Hamiltonians as complement the state of the art calculations. Using spin Hamiltonians and resonance concepts, we treat the spin distribution in triangular and hexagonal distorted graphenes. The polyacenes are taken as molecular models of organic conduction, bringing a fresh perspective in issues with both application relevance and heuristic meaning.

Development of Novel materials for High Efficiency Dye-Sensitized Solar Cells Call name:
PN-II-ID-RSRP-2012-1 -

Role in this project: Project coordinator

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners:

Affiliation:

Project website:

Abstract:

The project proposes a collaboration between established laboratories in Switzerland and Romania

in order to mutually enhance our research capabilities, facilities and expertise. In order to improve

the conversion efficiency and accelerate practical DSSCs, a thorough understanding of the

underlying photo-electrochemical processes is needed. This goal will be reached by combined

experimental and computational (density functional theory) studies. Interfacial processes between

TiO2 electrode, the sensitizer, the electrolyte and the counter electrode will be studied by various

experimental methods. DSSCs with high photovoltaic efficiencies will be fabricated.

Partner institution: Ecole Polytechnique Fédérale de Lausanne

A NEW GENERATION OF PARADIGMS IN THE MOLECULAR MAGNETISM AND MATERIAL SCIENCES. THE MAGNETIC ANISOTROPY IN COMPLEX UNITS, SUPRAMOLECULAR SYSTEMS AND AT NANO-SCALE. Call name: Complex Exploratory Research Projects - PCCE-2008 call
PN-II-ID-PCCE-2008-0239 2010 - 2013

Role in this project:

Coordinating institution: UNIVERSITATEA DIN BUCURESTI

Project partners: UNIVERSITATEA DIN BUCURESTI (RO); UNIVERSITATEA OVIDIUS DIN CONSTANTA (RO); UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI, CENTRUL DE EXCELENTA CNCSIS-CARPATH (RO); INSTITUTUL DE CHIMIE FIZICA I.G.MURGULESCU AL ACADEMIEI ROMANE, LABORATORUL DE CHIMIE COORDINATIVA (RO); UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI, CATEDRA DE CHIMIE FIZICA, TEORETICA SI CHIMIA MATERIALELOR (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA MATERIALELOR, LABORATOR DE FIZICA TEMPERATURILOR JOASE SI SUPRACONDUCTIBILITATE (RO)

Affiliation: UNIVERSITATEA OVIDIUS DIN CONSTANTA (RO)

Project website: http://stoner.phys.uaic.ro/projects/pcce_92010.html

Abstract:

The project draws a new axis among top subjects of the molecular magnetism, illuminating key factors such as spin coupling, magnetic anisotropy, relaxation and tunneling of magnetization, that govern special properties, like the single molecule and single chain magnet behavior. On the ground of recent achievements challenging such paradigms both in experiment (chemical synthesis, materials forging, physical measurements) and theory (quantum models and calculations) one delineates coherently new development areas. The structure of thematic and participations is interdisciplinary, well-tempered in the individual competences and collaboration links. The central idea stays in the detailed structure-property analysis in coordination spheres with intrinsic anisotropy (f- lanthanide complexes, d-transition metal ions like mn(iii), co(ii)) used as new building blocks in d-d, d-f and f-f systems. The project places on equal footing both the synthetic part, including the rational control of the assembling factors (in coordination, supramolecular or lattice systems) and the theoretical one, revealing the electron structure causalities of spin and orbital couplings, drawing landmarks on the way to engineering of special properties and applicability extensions in spintronics and nanodevices. By the attention devoted to the new case studies provided by the experimental part (coordination compounds and materials), we aim to fill the gaps separating the chemist’s vs. physicist’s approaches. The magnetic anisotropy understanding at microscopic and mesoscopic levels draws a new generation of problems in the modern magnetism. The team members have rich expertise, illustrated by series of papers published in journals of high impact, general (JACS, PHYS.REV) or specialized ones (coordination and theoretical chemistry, magnetism, materials), well perfected in international stages and having active interests in creating infrastructures for applied and academic research.

Design of novel sensitizing dyes for nanocrystalline solar cells on the basis of their electronic structure calculations Call name:
PN-II-Capacitati-M3 116/2008 -

Role in this project: Project coordinator

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners:

Affiliation:

Project website:

Abstract:

The main goal is to obtain and characterize efficient dye-sensitized solar cells using nanocrystalline

TiO2 based technologies. We will adopt a cross-disciplinary approach where physics and chemistry

are combined to develop new materials as TiO2 sensitizers. The approach will combine density

functional theory calculations with dye syntheses and characterization as well as device fabrication

and testing. To understand the mechanisms of light absorbtion and of electronic excitation of the

dye, as well as of the charge transfer to the oxide we propose the theoretical study of Ru- and

Os-complexes with ligands such as 2,2’-bipyridile, 4,4’-dimethylbipyridile, 2,2’-biquinoline,

phenantroline and porphyrins. We plan to simulate several sensitizing dyes for more efficient

DSSC. Complexes of Ru, Os, Rh, Ir, and Pt-ions will be studied.

Joint research project Romania-Ukraine. Partner institution: Cherkassy State University of Technology

Towards new materials for solar cells: calculations, synthesis and measurements Call name:
PN-II-Capacitati-M3 186/2009 -

Role in this project: Project coordinator

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners:

Affiliation:

Project website:

Abstract:

The main scientific goal is to synthesize and characterize new compounds and to study their suitabiltiy

as components of dye-sensitized solar cells. We propose the use of two new Pt complexes, with

pyramidalized olefins as ligands, to understand the mechanisms of light absorption and of electronic

excitation of the dye, as well as of the charge transfer to the oxide, in hybrid organic-inorganic photovoltaics.

Joint research project Romania - Cyprus. Partner institution: University of Cyprus

Înființarea și susținerea activităților Societății Antreprenoriale Studențești „Ovidius Innovation Center” - OIC-SAS Call name: Fondul de Dezvoltare Instituţională - FDI - Competiţia 2017
CNFIS-FDI-2017-0656 2017 -

Role in this project:

Coordinating institution: UNIVERSITATEA OVIDIUS

Project partners: UNIVERSITATEA OVIDIUS (RO)

Affiliation:

Project website:

Abstract:

Obiectivul general al proiectului îl constituie înființarea și susținerea activităților societății antreprenoriale studențești „Ovidius Innovation Center” în cadrul Universității Ovidius din Constanța.

Obiectivele specifice ale proiectului sunt:

1. Asigurarea cadrului organizatoric și logistic dar și a resursei umane necesare pentru funcționarea societății antreprenoriale studențești „Ovidius Innovation Center”.

2. Dezvoltarea de competențe și abilități antreprenoriale la studenți și absolvenți prin organizarea de evenimente de popularizare, ateliere de lucru de promovare a antreprenoriatului și de generare de idei inovatoare și elaborarea de materiale pentru cursuri de antreprenoriat.

3. Sprijinirea inițiativelor de afaceri ale studenților și absolvenților prin organizarea de sesiuni de formare și mentorat și a unei competiții pentru construirea și dezvoltarea unui model de afaceri.

Aceste obiective se încadrează în strategia de dezvoltare instituțională 2016-2020 a UOC, care are în vedere afirmarea universității ca pol regional de excelență în inovare, transfer tehnologic și antreprenoriat. Într-un sens larg, proiectul răspunde cerințelor Strategiei Naționale pentru Învățământul Terțiar 2015-2020 (pilonul 2 - Programe flexibile, relevante și de înaltă calitate, care să dezvolte competențele transversale și antreprenoriale, și pilonul 3 - Angajament strategic față de sectorul economic) și de Concluziile Consiliului privind antreprenoriatul în educație și formare 2015/C17/02.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects