BrainMap

Mr. Marius Ghiurea

PhD

Senior Researcher - Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Researcher

Curriculum Vitae (05/02/2024)

Expertise & keywords

Prototype coating system to reduce the CO2 footprint and environmental impact in shipping Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2021-0675 2022 - 2024

Role in this project: Key expert

Coordinating institution: QWERTY DEVELOPMENT MACADA-M S.R.L.

Project partners: QWERTY DEVELOPMENT MACADA-M S.R.L. (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://sparacom.ro/rezultate/ si https://sparacom.ro/date-generale/

Abstract:

SPARACOM is a complex solution for the transfer to the economic operator, in order to increase the competitiveness of the economic environment and the assimilation of market-oriented RDI results. The consortium involves the collaboration between an innovative company and a large research institute in the field. The proposal aims at the efficient maximization of the financing instrument (technological maturation of TRL4 to TRL6; it starts from the technology validated within PN-III-P2-2.1-PED-2016-1332, 84PED, financed by UEFISCDI; the use of an infrastructure at international level; SMEs with high innovative potential; avant-garde technological solution, an opportunity at the level of the international market; connecting national applied research to the national and international market). The budget is balanced by allowing adequate and flexible resources for better management and contingency plans. To maximize the final results some activities and budgetary resources from outside the project are committed to increase the visibility and impact of research. The CO and P1 research team implies an important institutional character: members from several departments and research teams together with the valorization of competencies. The technological approach involves advanced hybrid antifouling systems (and acting in a sequential mode) but also a self-repair system with potential in freshwater and marine environments (a major challenge in the field). The expected results involve both TRL technology and at least: a paper at scientific events, a paper sent for publication to an ISI publication, a patent application, a web page.

Eco-friendly nanocomposites based on bio-PA and bio-fillers for injected auto parts Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-0795 2022 - 2024

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO)

Affiliation:

Project website: https://icechim.ro/project/econano4auto/

Abstract:

The ECONANO4AUTO project offers an innovative and efficient solution for the field of smart specialization - Energy, environment and climate changes, namely reducing the CO2 footprint and accumulations of polymeric waste, by developing of new and innovative technology for obtaining of new polymer bio-nanocomposites based on bio-PA and keratin/ nanoparticle hybrids, lightweight and with improved thermal and mechanical properties. Starting from high-performances bio-PA10,10 and a natural waste (chicken feathers) the project will provide at the end a viable, low cost and eco-friendly solution for effective using of chicken feathers and reducing of impact on environmental pollution. The developed technology will be validated in laboratory conditions to obtain parts by injection moulding. A toxicological study will be carried out regarding the nanomaterials action on the epidermal and pulmonary cells and a methodological guide will be elaborated regarding the prevention of the risks related to the work with nanoparticles. The partnership for this project involves 2 R&D National Institutes, well known in Romania and abroad, competent in the project field and with scientific and technical potential for development and characterization the new technology for obtaining bio-polymer nanocomposites.

Biopolymer structures obtained by plasma treatment for wounds healing Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2021-2559 2022 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE MEDICO-MILITARA „CANTACUZINO” (RO)

Affiliation:

Project website: https://icechim.ro/project/biopolymer-structures-obtained-by-plasma-treatment-for-wounds-healing-bioplasm/

Abstract:

Chronic wounds, severe burns or infected wounds are among the most painful diseases that require long-term expensive treatment. Currently, the clinical management of chronic wounds is difficult due to the increasing risk of infection with antibiotic-resistant bacteria and the shortcomings of current therapies. A novel technology for the manufacture of bilayer wound dressings, based on nanocellulose and cold plasma processing, will be developed in BIOPLASM project. The scope of the project is to obtain effective dressings for the treatment of infected wounds by developing antibacterial nanocellulose nanocarriers deposited on an aliphatic polyester substrate.

The use of cold plasma for nanocellulose and biopolymers processing in view of medical application is an effervescent field, with important benefits related to eco-friendliness, lack of secondary or waste products, sterilization and large functionalization capabilities. Cold plasma treatment of liquid suspensions of nanocellulose is a concept developed by ICECHIM and INFLPR in a previous project. This will serve as a starting point together with the functionalization and processing of nanocellulose and aliphatic polyesters for building a new technological approach to fabricate bilayer wound dressings. The new technology will be validated by in vitro and in vivo studies. The project will be implemented by a skilled group of researchers from ICECHIM, INFLPR and Cantacuzino Institute.

Integrated use of the next generation plant biostimulants for an enhanced sustainability of field vegetable high residue farming systems Call name: EEA Grants - Proiecte Colaborative de Cercetare
RO-NO-2019-0540 2020 - 2024

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); Norwegian Institute for Water Research (NO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); Norgenotech AS (NO); ENPRO SOCTECH COM SRL (RO); AMIA INTERNATIONAL IMPORT EXPORT S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim.ro/project/stim4plus-en/

Abstract:

The project addresses mainly the thematic area of Biotechnology, more exactly the key topic Biotechnology for agriculture, aquaculture, forestry and biomass production. The biotechnological solutions which STIM4+ project proposes to develop are intended to compensate the negative effects of the low-input, high-residue sustainable vegetable production systems. These proposed biotechnological solutions are related to the use of the next generation plant biostimulants. Plant biostimulants represent an emerging class of agricultural input, which protect plants against abiotic stress, enhance / benefits nutrients uptake and improve yield quality . The proposed plant biostimulants to be used for an enhanced sustainability of field vegetables grown in a high residue system are including into all classes / subclasses mentioned in the new EU Regulation 1009/2019. The multi-functional Trichoderma strains-based plant biostimulants (a microbial plant biostimulants) will be included into a glycodinameric, chitosan based bioactive (micro)hydrogel formulation. Decoration of microgels with anchor peptides will be used as a (micro)hydrogel tackifier on the plant residues. The bioactive hydrogel is based on an organic plant biostimulants (chitosan), which will be used to generate a biocompatible 3D porous structure, thermo- and pH-responsive and with a hydrophilic – hydrophobic segregation feature. This hydrophilic – hydrophobic segregation (micro)hydrogels will be used for embedding hydrophobic mimetic strigolactones. Propper application technologies of such smart formulated hydrophobic molecules will be developed, to exploit strigolactones both functions, as exo-signals for a better harnessing of beneficial microbiome and as cue for deleterious organisms (e.g. to induce suicidal germination of parasitic plants). The smart formulated bioproducts / agricultural inputs and the agricultural practices intended to exploit their specific features of such bioproducts are an example of biotechnologies for agriculture. The natural strigolactones mimics will be a part of the microbial standardized extract, which we intend to produce from microalgae culture and which is another example of organic plant biostimulant. This microbial standardized extract will include natural strigolactones, polyamines and betaines. Both strigolactones and polyamines are exo- and endo-signals. As exo-signals, both strigolactones and polyamines have been demonstrated to enhance mycorrhizae hyphal branching and root colonization. As endo-signals, both strigolactones and polyamines are involved in plant stress responses. Betaine also supports plant response to stress, especially to drought. Strigolactone mimics used for laboratory screening will be synthetized based on a rational bio-design. The inorganic plant biostimulants are represented by selenium, as zerovalent nano-selenium. A large body of evidence demonstrates that selenium acts as a plant biostimulant. Selenium protects plants against abiotic stress, especially drought, enhances / benefits nutrient uptake and improves edible yield quality. Nanoselenium (zerovalent) particles show a much lower environmental impact and an improved efficiency compared to other selenium species. Application of selenium nanoparticles reduces the risk of accumulation of polyamines in the edible yield. From a food safety point-of-view, accumulation of polyamines in vegetables grown into HV mulch could have some carcinogenic effects, because polyamines were found to support proliferation of various tumor cells.

The project is an interdisciplinary one and address also other key topics as Environmental impact and risk assessment of the modern, new and emerging technologies and products. Safety and environmental impact of the new developed products will be determined by a state-of-art 3R techniques, by Norway partners. The project contributes to the objectives and the priorities of the call. It supports research cooperation between Romania and Norway and consolidate a strategic partnership.

Better harnessing of Trichoderma biotechnological potential for biorefinery and as plant biostimulants by controlled development and biosynthesis Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-2780 2021 - 2023

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: https://icechim.ro/total

Abstract:

Project TOTAL aims to investigate and integrate abiotic modulation and epigenetic control of Trichoderma strains within the context of Trichoderma interactions with biomass and living matter, for better harnessing of Trichoderma biotechnological potential. The specific objectives of the project are: (i) To establish and optimize the combined effects of light and nutrients on expression of proteins acting on plant cell walls and spore formation by Trichoderma strains; (ii) To optimize the deconstruction of plant cell walls by Trichoderma secreted proteins; (iii) To synergize the plant biostimulants effects of Trichoderma chlamydospores. The current approaches targeted the optimization of Trichoderma utilization either in agriculture or in biorefinery. The optimization of culture conditions have been in general focused either on improving sporulation to be used in biopesticides formulations or on the enzyme production for biomass deconstruction. Secondary products have been usually disregarded and discarded. An integrative technology to benefit from both advantages that Trichoderma offers has not been established. We plan to integrate the investigation of the fundamental aspects of Trichoderma development (light-, nutrient- and stress- mediated chlamydospore formation; cell signaling pathways; epigenetic effects) with its growth optimization for the use in both biomass valorization and plant biostimulant formulations.

Nanodielectrics for underwater microstrip antenna substrates Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4687 2020 - 2022

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation:

Project website: http://nadumas.elmat.pub.ro

Abstract:

Patch (or microstrip) antennas are among the most common antenna types in use today, because they can provide high performances in small packages (especially for modern fixed and mobile wireless devices), high gain, or light weight, or handle high power levels. The choice of the dielectric substrate material plays a key role in the size and performance of a patch antenna, such as achieving maximum gain at the desired radio frequency (RF). As for RF for underwater communication they should be as low as possible because of the high losses due to conductivity of sea water, which leads to the increase of the absorption loss at high frequencies. The proposed project aims to design and develop new polymer nanocomposites as substrate materials for patch antennas working at low frequencies for wireless data and power transfer in water. Thus, the main project scope is to obtain nanodielectrics with high dielectric constant and in the same time with very low dielectric losses, together with all the other properties required for patch antenna substrates: homogeneity, dimensional stability with processing and temperature, humidity and aging, resistance to chemicals, impact resistance, formability, bonding ability, foil adhesion etc. The variation of the dielectric properties with frequency and temperature will be analyzed on the proposed nanodielectrics by broadband dielectric spectroscopy in the range 10-6 – 109 Hz and -100 – 400 °C.

Therefore the demonstration model of the NaDUMAS project consists in a technology for nanodielectrics for patch antenna substrate. First, several polymer nanocomposite will be proposed and tested to analyse their potential as substrate for patch antennas. Then, the best nanodielectrics will be in depth investigated regarding their dielectric, mechanical and thermal properties. Finally, selected nanodielectrics will be used as substrate to prepare patch antenna structures to be tested and compared with commercial available antenna substrates

Biogenic nano-system for targeted delivery of bioactive ingredients on dysbiosis biofilm involved in gingivitis and periodontitis Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-4527 2020 - 2022

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: https://icechim.ro/project/bionanogum-en/

Abstract:

BioNanoGum project proposal aims to develop an innovative biogenic nano-system for resolution of dysbiosis oral biofilms and inflammation involved in gingivitis and periodontitis, based on an innovative bacterial nanocellulose - fungal (nano)chitosan stimuli-responsive hydrogel, biogenic selenium nanoparticles (bioSeNPs), and hollow pollen shells filled with biogenic silica nanoparticles (bioSiOxNPs). Gingivitis and periodontitis affect more than 30% of globe population and can lead to teeth loss, but also other complications and severe diseases (Alzheimer, diabetes, autoimmune diseases). SeNPs, silicic acid released from SiOxNPs, and chitosan nano-structures determine (frank) resolution of dysbiosis biofilms and inflammation. However, there are also several drawbacks such as a very narrow physiological window (in the case of Se), or induced inflammation through a MAMPs similar mechanism, mediated by the Toll-like receptors (in the case of SiOxNPs). New formulations are needed in order to reduce risks of negative effects and to optimize the beneficial effects. BioNanoGum will use compounds acting complementary to SeNPs, which will lead to the reduction of Se dose. The pollen shells, obtained by Kombucha fermentation, will be used as encapsulation carriers for SiOxNPs, which allows bearing benefits from the anti-inflammatory, anti-bacterial and wound-healing effects of the silicic acid slowly released from bioSiOxNPs. The biogenic nano-system will deliver different components into a complementary manner and will act both on the resolution of pathogenic biofilms and on that of inflammation. BioNanoGum involves the niche between biotechnology and nanotechnology with health applications. This niche market has a significant growing potential, because it addresses several of the main health problems in the European Union and worldwide, from the beginning of the 21st century : an ageing population, with an increased incidence of non-communicable / chronic disease.

Biorefining of the side streams resulted from cyprinids commercialization Call name: P 2 - SP 2.1 - Proiect de transfer la operatorul economic
PN-III-P2-2.1-PTE-2019-0181 2020 - 2022

Role in this project:

Coordinating institution: MEDICA FARMIMPEX S.R.L.

Project partners: MEDICA FARMIMPEX S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://info.pro-natura.ro/colstim/

Abstract:

The aim of the project is to increase the competitivness of the coordinating company Medica Farmimpex and of the economic agents beneficiaries of the products obtained by the project, by assimilating some CDI results and by strengthening the partnership with research units in the fild of Bioeconomy-Biotechnology.

As result of this project it is expected to obtain high value-added products, trough an integrated extractive biotechnology, from the side streams of the commercialization of freshwater fish (cypridins).

Through the biotechnology that would be carried out at industrial level by the project coordinator, they will recover from the lateral flows of freshwater fish processing: collagen hydrolysate (nutraceuticals for human use) and gelatin like polypeptides (plant biostimulants). The remaining residue after the extraction of the peptides is processed into bone flour which is an essential nutritional supplement for feeding predatory fishes. Each of these products has a high use value associated with a significant market value.

The objectives of the project are: (i) to develope a pilot installation to obtain high valued products from the side streams of the fish commercialization; (ii) to validate the integrated technology in industrial environment; (iii) to demonstrate the functionality of the technology in the industrial environment by characterising and testing the obtained high added - value products.

The innovative character is given by the integrated concept of total capitalisation of the fish by-products. Another innovative aspect is the development of the quality assurance system, using NIR spectroscopic sensors coupled with a chemometric analysis.

The project parteners are INCDSB and INCD-ICHECHIM. INCDSB has the necessary expertise to transfer the technology for obtaining collagen hydrolysates. INCD-ICECHIM has the expertise to obtain and characterise the peptides as plants biostimulants.

Emerging technologies for the industrial capitalization of 2D structures (graphene and nongraphenic) Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0387 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR, PLASMEI SI RADIATIEI - INFLPR RA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU TEHNOLOGII IZOTOPICE SI MOLECULARE I N C D T I M (RO); UNIVERSITATEA DIN CRAIOVA (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=49

Abstract:

EMERG2Ind is a complex solution that responds to the needs of Romanian research on one side through a institutional management and development mechanism, but at the same time it is a complex interface tool for the Romanian automotive industry as a development engine and integrator for the horizontal and vertical integration of the Romanian economic resources. International expertise is available in an attempt to develop concrete solutions in the country. Emerging technologies are being developed up to TRL4 and TRL5, through complementary harmonization of three strategic subprojects. The complex project approach is regional and institutional with cumulative indicators that fully meet the requirements and seeks to maximize the use of the funding instrument.

Closing the bioeconomy value chains by manufacturing market demanded innovative bioproducts Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0569 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); UNIVERSITATEA "DUNAREA DE JOS" (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); UNIVERSITATEA AUREL VLAICU ARAD (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=51&lang=ro

Abstract:

Agriculture and food industry in Romania generates large amounts of co/by-products, which are not used and turn into wastes, with negative impacts. The approach of the project PRO-SPER is to develop integrated processes, flexible and interconnected, to transform a number of agro-food by-products in bio-products, with market demand. This approach facilitates the achievement of project goals, complex-coordination and linking of the research organizations that are members of the Consortium, INCDCP-ICMPP, UDJ, ICECHIM, INCDSB and UAV, for improving their institutional performance in the field of nano-and bio-technologies of their application into bioeconomy.

The overall objective of the project PRO-SPER is to increase the impact of research and development activities and innovation of the RDI institutions, by developing and harnessing innovative technological solutions for bio-nano-processing of several by-products from the bioeconomy value chains, for recovering and/or formation of value-added components and their use in order to obtain products with high added value.

Expected results through the implementation of the project (21 new jobs, 23 national patent applications and international patent applications 6 EPO/WIPO; 10 technologies/new products resulting from the project, at a level of technological maturity to enable taking over by the operators, 5 services research and technological research services 10 cheques, 10 experiments cheques services

80 internship of young researchers from and within partner institutions, 50 visits for developing new techniques for working jointly in the Consortium, 30 training internships for new employees, 28scientific papers, 1 joint program CDI, in line with the development plan of institutional partners) have a significant impact on the capacity-building of the partners in the Consortium.

Energetic efficiency biogas plants improvement by integrated system: biogas-microalgae-biofuels in frame of biorefinery concept (AlgalBiogasConceptEnergy) Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0541 2018 - 2021

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU INGINERIE ELECTRICA ICPE - CA BUCURESTI (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU CARTOF SI SFECLA DE ZAHAR-BRASOV (RO); UNIVERSITATEA PETROL GAZE PLOIESTI (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.icechim-rezultate.ro/proiect.php?id=38&lang=ro; http://www.icechim-rezultate.ro/proiect.php?id=39&lang=en

Abstract:

The complex project propose the development and demonstration of innovative technologies to optimize the biogas plants by integrating the open ponds for microalgae cultivation using the digestate resulted from anaerobic digestion as a culture medium. The integral valorization of microalgae biomass consists in: obtaining of algal extracts (for co-digestion), lipid fraction (for biofuels) and spent biomass (co-digestion substrate); advanced separation and valorization of biogas by carbon dioxide conversion to biomethane; biorefining of the solid digestate and lipid fractions obtained from algal biomass into biochar, fuel components, bitumen fluxes, biohydrogen and liquefiable gaseous fractions. As results of this project will be: a demonstrated technology at TRL 6 level within the biogas-microalge integrated and an experimental stand for the evaluation of biomethane and liquefied gaseous hydrocarbons combustion efficiency and emission control.

Production of ferulic acid, 2,3 Butanediole and microbial plant biostimulants from lignocellulosic biomass by a two-step cascading process Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-FACCE-SURPLUS-DEBUT 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); ENPRO SOCTECH COM SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=46&lang=ro

Abstract:

The DEBUT project aims to develop a small biorefinery process, with two steps: 1) biomass pre-treatment with natural deep eutectic solvents (NaDES); and 2) one pot production of a versatile chemical, 2,3 butanediol (2,3-BD), from NaDES pre-treated lignocellulose biomass, by simultaneous saccarification and fermentation (SSF), performed by a plant biostimulant microbial consortia. The main biochemicals resulting from the biorefinery process are phenolic acids, specially ferulic acid, and 2,3-BD. Phenolic acids address mainly health and wellness-related industries, whereas 2,3-BD is a versatile chemical, with a fast-growing market. The proposed biorefinery process produces also agricultural inputs such as lignin, minerals and microbial plant biostimulants. A first project novelty is related to the use of a plant biostimulant microbial consortium for simultaneous saccarification and fermentation of lignocellulose. According to our knowledge such approach has not been done yet. On such process there are no by-products – recalcitrant lignocellulose, not converted to 2-3 BD, together with embedded microbial biostimulants biomass, is a useful agricultural input - a microbial plant biostimulant. Process up-scale to TRL5 is done also in an innovative manner, through adaptation of the already known equipment to newly developed technology. For NaDES extraction we propose to use the continuous operated reconfigurable columns systems, applied for decades for various types of extraction (e.g. for extraction of soluble from coffee). For SSF with microbial plant biostimulant consortium we propose the use of vacuum operated ploughshare mixer. This approach will ensure not only a better recovery of volatile 2,3 BD, but also a higher specificity of the fermentation medium, due to micro-aerobic conditions. The DEBUT project proposes a new approach of small scale biorefinery, compatible with a farm facility, which valorises agricultural side streams, with recovery of minerals and lignin (main precursor of soil organic matter) for agricultural use, and production of an innovative agricultural input, a microbial plant biostimulant. The project proposes a biotechnological two step cascading process, which converts excess lignocellulosic biomass into biochemicals (phenolic acids, 2,3 B-D), with added-value and fast-growing market. The main innovative solutions, NaDES and microbial plant biostimulant, are investigated for their potential adverse effects by a battery of state-of-the art techniques, in an trans-national partnership, to ensure that they do not affect natural ecosystem productivity.

Innovative green technologies for valorisation of lignocellulose Call name: P 1 - SP 1.1 - Proiecte de cercetare pentru stimularea tinerelor echipe independente
PN-III-P1-1.1-TE-2016-2518 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=29&lang=en

Abstract:

The scientific scope of the INTELIGRENCE project is to develop an innovative green technology, based on natural deep eutectic solvents (NADESs) and enzymatic processes, for multi-stage cascading use and valorisation of lignocellulosic biomass. The following interrelated specific objectives will be addressed: (1) to elaborate NADESs with high feruloyl esterase (FAE) compatibility and ability to extract ferulic acid (FA) from biomass; (2) to develop NADESs for cellulose valorisation into nanocelullose and the subsequent saccharification of the polysaccharides; (3) to investigate and optimize the use of selected NADESs in a multi-stage cascading processing of a lignocellulosic substrate. The project brings several innovative elements: the first time use of a high-throughput experimentation (HTE) approach for characterization and optimization of NADESs-based formulations for lignocellulose processing; in-situ lipophilisation of FA and generation of secondary (hydrophobic) NADESs from FA; the use of NADESs in association with enzymatic cocktails incorporating the recently discovered lytic polysaccharide monooxygenases (LPMOs) during the second step of the multi-stage cascading approach. The applied direction is related to the high added value of the main products (ferulic acid and nano-cellulose) intended to be obtained from lignocellulose by the proposed cascading NADES-enzymes treatment approach. Ferulic acid is an ideal precursor for the production of bio-vanillin and it exhibits a wide variety of biological activities, having a market which will exceed $100 million (US), mainly due to the increased demand for anti-aging serum based on ferulic acid. Nanocellulose market will exceed $250 million (US) in 2023, due to applications related to composites, packaging, coatings, biomedicine and automotive. The new scientific data will be relevant also for the biological significance of NADESs that are formed from components which are normally present in biological systems.

Development of a demonstrator to produce next generation plant biostimulants based on root exudates Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-MANUNET III-DEMETRE 2018 - 2020

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CHEMI CERAMIC F SRL (RO); RODAX IMPEX S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=47&lang=ro

Abstract:

Plant biostimulants are a new class of agricultural inputs, which increase nutrient uptake and nutrient use efficiency, improve plant tolerance to abiotic stress and enhance crop quality. The DEMETRE project aims to develop and to validate devices, tooling and equipment needed to (bio)manufacture a new product, from the (emerging) next generation of plant biostimulants. The proposed new plant biostimulants product is based on concentrated bioactive compounds from root exudates. The main innovation overcurrent state-of-the art is related to the new, flexible (bio)manufacturing method, which join two known products in a two-in-one synergic product. During its use, the proposed two-in-one product will fulfill two functions: as soil conditioner and as reservoir for the slow release of the selected bioactive compound(s). The needs addressed by the project DEMETRE are related to: (i) agricultural market requirements for new inputs, reducing the consumption and the environmental impact of agrochemicals while maintaining / increasing profitability; and (ii) societal requirements for a circular (bio)economy, wherein the loop is closed due to the valorization of agroindustrial byproducts. In the last years the interest of the economic agents and researchers for the development of new, more active plant biostimulants have been growing. Such active ingredients were proposed to be searched among exosignals, which regulate the plant – beneficial microbes interactions. Root exudates are a source of chemical signals shaping rhizosphere interactions, thus are a logical target to produce next generation plant biostimulant.

Nanocellulose 3-D structures for regenerative medicine Call name: P 4 - Proiecte de Cercetare Exploratorie
PN-III-P4-ID-PCE-2016-0431 2017 - 2019

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=35

Abstract:

Regenerative medicine and tissue engineering may offer new hope of life in case of loss or malfunction of a tissue or organs. One of the key elements in tissue engineering is the three-dimensional (3D) scaffold which provides structural support for cell attachment, proliferation and differentiation. Polymer scaffolds are preferred in tissue engineering to avoid problems related to donor immune rejection and pathogen transfer. Cellulose, the most abundant natural polymer on earth, is an almost inexhaustible source of valuable materials and has gained high interest in the form of nanocellulose (NC). NC stands out for its high crystallinity and mechanical strength, good biocompatibility, high water-holding capacity and large surface area and it has been intensively studied for medical applications because it does not cause toxic or allergic side effects in contact with living tissue. 3D scaffolds should possess a network of interconnected pores to permit cell migration, diffusion of nutrients and clearance of wastes, they must be able to support cell adhesion and promote cell growth and they must have balanced stiffness-toughness properties to support and transfer loads. To meet all these requirements in porous 3D scaffolding, CELL-3D has as main objective to design new nanocellulose 3D structures that can be applied in tissue engineering by: a). synthesis and characterization of nanocellulose 3D structures using surface functionalization and crosslinking; b). synthesis and characterization of 3D structures from nanocellulose - biopolymer composites; c). designing new processing techniques for 3D nanocellulose structures. Biopolymers such as polyhydroxyalkanoates and other aliphatic polyesters with good elongation and flexibility will be used to obtain highly porous 3D composite structures.

A next generation plant biostimulant based on strigolactones included into stimuli responsive nanoformulation Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-INCOMERA-BENDIS 2018 - 2019

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL DE CHIMIE MACROMOLECULARA "PETRU PONI" (RO); ENPRO SOCTECH COM SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=50&lang=ro

Abstract:

The BENDIS project aims to integrate technologies for the industrial production of a next generation plant biostimulant based on strigolactones (SL) analogs and/or mimics, included into a stimulus-controlled release nanoformulation. A better harnessing of exogenously applied SL analogues/mimics requires such formulations, which protect SL from rapid degradation and promote their steady release at the biologically active concentrations under controlled conditions – i.e. roots mediated pH changes in the soil. The nanoformulation includes mesoporous nanosilica, loaded with a hydrophobic "green" solvent with dissolved SL analogues/mimics. Mesoporous nanosilica particles are decorated with humic acids, wherein SL are embedded. Humic acids are immobilized on mesoporous silica through an aminopropyl bonding.

A next generation plant biostimulants product Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0253 2017 - 2018

Role in this project:

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); CHEMI CERAMIC F SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://icechim-rezultate.ro/proiect.php?id=33

Abstract:

This project aims to develop and to validate a new product, from the (emerging) next generation of plant biostimulants. This new product includes concentrated active ingredients, from a new bio-resource, and a carrier, acting itself as a plant biostimulants. Plant biostimulants assure sustainable intensification of agricultural production, in face of major challenges. The main project novelty is related to: (i) the active ingredient concentration process, from a new bio-resource, assisted by a new electrochemical technique, for peroxynitrite determination and (ii) the formulation process, wherein a carrier with biostimulants characteristics is used. The existing category of non-microbial plant biostimulants are extracts of organic fertilizers / organic amendments, traditionally used in agriculture. Organic non-microbial plant biostimulants shall contain “carbon of solely animal or plant origin” (COM (2016) 157), thus the next generation of more active and more efficient plant biostimulants will be concentrated bioactives from the present / existing extracts. Project NEXUS objectives are: (i) to optimize product components and to improve compatibility; (ii) to develop demonstration model, through components integration and (iii) to test and to validate demonstration model, on laboratory conditions. Objectives are related to different TRL. Improved compatibility and optimal composition of microalgae extract (1st objective) allow critical function and/or characteristic analysis and improvement (TRL 3). Components integration (2nd objective) and product testing in laboratory conditions (3rd objective) permit technological development till TRL 4. The project work plan is divided into 6 activities (Work Packages): WP1 Humic acids loaded macroporous ceramics; WP2 Optimized microalgae concentrated extract; WP3 Concentrated bioactives inclusion into humic acids – porous ceramic; WP4 Bioassay of biostimulant activities; WP5 Dissemination and exploitation; WP6 Management.

MULTIFUNCTIONAL AND INNOVATIVE PRODUCTS FOR SAFE AND BIOENHANCED FUNCTIONAL FOOD FROM NEWLY CULTIVATED PLANTS IN ROMANIA Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0995 2014 - 2017

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); HOFIGAL EXPORT IMPORT SA (RO); CHEMI CERAMIC F SRL (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://produse.multifunctionale.icechim.ro

Abstract:

Thematic area of the project proposal is in the field of functional foods destinated to maintain human health in concordance with research theme 5.1.6. Functional foods to maintain human health and prevent diseases, Domain 5. Agriculture, food safety and security.

The general project objective is to develop multifunctional and innovative products for protection of nutraceutical plants newly introduced in Romania (Momordica charantia and Passiflora incarnata) and to stimulate concomitantly formation of biologically-active compounds in these plants, at stable levels and with reproducible biological effects. The specific innovative project objectives are: 1. development of multifunctional for treatments of soil and in vegetation, based on: (a) consortia of Trichoderma strains; (b) porous ceramics with high bioavailability of silica; (c) essential oils included in mesoporous silica; 2. Testing products, developing methods of application and integrating them with the sustainable cultural technology of nutraceutical plants; 3. characterization of functional foods through in vitro alternative tests on human cell cultures and highlighting the biological role of silica forms accumulated in treated plants in animal cells; 4. results exploitation by protection of intellectual innovative solutions after techno-economical analysis and opportunities of results exploitation.

Products based on consortia of Trichoderma strains and essential oils have multiple actions as: plant protection agents towards biotic stresses (phytopathogens, pests), elicitors of plant defence response, limiting agents for the negative effects of ethylene on roots and growth promotor of plant nutrition, mainly with nitrogen.

Porous ceramics containing silicaxerogel, applied as soil treatment, work as a matrix for controlled release of nutrients with high bioavailability and have role to compensate losses of plant metabolic energy due to the synthesis of secondary metabolites and to supply orthosilicates with high bioavailability.

Silicon with high bioavailability supplies also mesoporous silica as a carrying for controlled release of essential oils. The silicon’s role as an important element for plants is to activate and balance - concomitantly and non-antagonistically – the different ways of plant defence system and of stress hormones biosynthesis (salicylic acid, jasmonic acid and ethylene/abscisic acid) in plant pathosystems.

This project proposes for the first time to study interaction of silicon, Trichoderma and essential oils treatments, protection agents with multiple roles, which activates simultaneously plant defence response. It is the first proposal aiming the development of some products with applicability directly into practice, in which silicon is controlled released from supports, having concomitantly the functional role as a matrix, from which nutrients and volatile oils are smart-delivered, in this why pointing out the possibility of practical use of silicon in order to balance the main signalling pathways in plant defence response, integrated with elicitors for obtaining high productions with raised phytonutrients level.

The highlight of silicon’s role in animal and plant organisms (having into account the unity in diversity of the life world), the (meso)porous silica forms as a support for controlled release of some active ingredients and of bioavailable silicon, compatibility of the Trichoderma consortia with the other products for the directed activation of plant resistance, will be the coagulation axis of this trans-disciplinary approach, revealing - also - the existence of synergies between partners in the frame of MAIA Project.

Eco-friendly food packaging from last generation multifunctional bioplastics Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-1569 2012 - 2016

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); METAV - CERCETARE DEZVOLTARE S.R.L. (RO); INSTITUTUL DE CERCETARI PRODUSE AUXILIARE ORGANICE S.A. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.bio-multi-pack.icechim.ro

Abstract:

The project proposes to carry out a technology for obtaining multifunctional materials based on last generation of biopolymers and bioadditives melt processable into catering food packaging. These packages will comply with the food safety conditions and will have physical – mechanical properties proper to the plastic products that are generally of commodity nature. The national and international novelty and added value of the project is determined by the originality of the propose new conceptual models for realising of new materials with improved thermal stability, small hygroscopicity, melt processable into catering food packaging. The elaboration of new solutions needs inter and transdisciplinary knowledge of chemistry, physics, physics and chemistry of polymers, mathematical statistics, process engineering, scale up and economics. The new technology has a great applicative potential and can be applied on the same industrial platform or on different platforms. All the novelty solutions will be disseminated and will be patented. At present on the Romanian market one can find only packaging made from imported oxobiodegradable pellets which has limited biodegradability. The realising according to the proposed new technology products which in nature will be totally destroyed in a very short time, would turn into the advantaje of beeing the only supplier, on the Romanian market for totally biodegradable products. The technology can be internationally applied by country with the same envoiroment problems as Ramania. The project consortium is formed from 4 partners: ICECHIM (CO), Politehnica University Bucharest (P1), SC Metav CD –SA (P2) and SC ICPAO SA (P3) with complementary expertise. The project manager is doctor and fulfill the eligibility conditions. P1 and P2 has project responsable that are doctors. Because of the great interest for the proposed subject P3 co–funded with 25 % from the entire project fund.

Thermosensitive energy saving systems with tailored solar reflecting/absorbing properties for construction structures Call name: Joint Applied Research Projects - PCCA-2011 call, Type 2
PN-II-PT-PCCA-2011-3.2-1391 2012 - 2016

Role in this project: Key expert

Coordinating institution: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti

Project partners: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); CHIMCOLOR S.R.L. (RO)

Affiliation: Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Project website: http://www.thermosolar.roit.ro

Abstract:

In principle thermochromic and thermotropic systems can function as energy saving systems. For high temperatures, during summertime thermochromic coatings have the ability to reflect solar energy, reducing the surface’s temperature; while in wintertime absorb solar energy, increasing the surface’s temperature as reversible color change takes place. Applied thus on external building surfaces, they have the potential for the reduction of heating and cooling loads, contributing to the reduction of urban temperatures, fight heat island and reduce air pollution.

Color-changing compounds have become increasingly important in recent years in the study and the production of thermochromic coatings that is coatings which respond thermally to their environment, changing reversibly their color from darker to lighter tones as temperature rises. The novelty comes from the use concomitant of thermotropic hydrogels which respond thermally by changing transparency from total transparent to translucent. Combining these features of termotropic hydrogels and thermochromic dyes we can obtain complex thermosensitive systems that respond to an increase in temperature by switching the color hypsochromically while accompanied by a change in transparency of the hydrogels.

During the project we intend to develop thermosensitive energy saving coatings that action on the entire Vis-NIR range and are most typically applied to roofs but additionally can also be applied to exterior and interior walls in much the same way. Thermosensitive coatings that will aim to obtain change reflectivity and color as a function of temperature, present enhanced weathering and durability and may be in any suitable formulation for application on roofs or walls such as water-based, oil-based, epoxy-based or acrylic-based formulations.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects