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Romania
Citizenship:
Ph.D. degree award:
2000
LACRAMIOARA
POPA
Professor
-
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"
Researcher | Teaching staff | Scientific reviewer | PhD supervisor
Web of Science ResearcherID:
K-9739-2019
Personal public profile link.
Curriculum Vitae (13/02/2024)
Expertise & keywords
Quality by design
chitosan materials
Wettability
pharmaceutical powders
superficial properties
Superhydrophobic materials
wetting properties
Hydrophobic surfaces
Methodology
scientific tools
Scientific literacy
Scientific research
Projects
Publications & Patents
Entrepreneurship
Reviewer section
New methods of pregnancy monitoring and prenatal diagnosis
Call name:
P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0820
2018
-
2021
Role in this project:
Key expert
Coordinating institution:
INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD
Project partners:
INSTITUTUL NATIONAL DE CERCETARE- DEZVOLTARE PENTRU MICROTEHNOLOGIE - IMT BUCURESTI INCD (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (RO); INSTITUTUL CLINIC FUNDENI (RO); INSTITUTUL NATIONAL PENTRU SANATATEA MAMEI SI COPILULUI "ALESSANDRESCU-RUSESCU" BUCURESTI (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO)
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (RO)
Project website:
https://www.imt.ro/mimosa/
Abstract:
The Complex Project „ New methods of pregnancy monitoring and prenatal diagnosis” proposes to define and develop new biomedical devices for pregnant women and foetus monitoring, with the purpose to avoid life-threating complications for both the mother and the child.
It will be developed through four Component Projects:
1. Prenatal non-invasive screening, using cell free fetal DNA, extracted from the mother’s blood. It will develop a chip for the non-invasive detection of the SRY gene, together with a working protocol for a new type of non-invasive analysis for the early prenatal diagnosis.
2. Non-invasive microsensors for continuous glucose monitoring during pregnancy – proposes the technology development for a non-invasive glucose sensor to measure the glucose level in saliva. The project will support the continuous monitoring of pregnant women, avoiding dangers effects coming from the invasive methods (inflammations, infections).
3. Evaluation of premature birth risks due to the HPV-EVA-RINA infection. The project will develop clinical studies related to the HPC infection involvement in triggering premature birth, using genotyping microarray-type structures;
4. Wireless multi-sensor system for foetal activity and uterine contractions monitoring and classification during pregnancy – aims to develop an intelligent system, containing a wireless network of wearable sensors and a main unit for signal processing and analysis.
The complex project description includes the novelty elements, detailed activities description, the working procedures within the consortium, expected results and deliverables. The deliverables has an average TRL 5, which means all four component projects will have a high technological level and the result’s maturity will reach at least successful laboratory testing.
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OPTIMIZATION OF THE MODERN TECHNOLOGY FOR PROCESSING BREWING SPENT YEAST AND OBTAINING OF DERIVED PRODUCTS
Call name:
P 2 - SP 2.1 - Transfer de cunoaștere la agentul economic „Bridge Grant”
PN-III-P2-2.1-BG-2016-0308
2016
-
2018
Role in this project:
Key expert
Coordinating institution:
UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA
Project partners:
UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI (RO); UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); PHARMACORP INNOVATION S.R.L. (RO); UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); AGSIRA SRL (RO)
Affiliation:
UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO)
Project website:
http://www.usamv.ro/dgpcsa-cdi/optimizarea-tehnologiei-moderne-de-procesare-drojdiei-uzate-de-bere-si-de-obtinere-produselor-derivate-biodryyeast/
Abstract:
The consortium consists of five research organizations that aim to obtain new products through optimization and validation of technologies, as well as to provide recommendation for the modernization of the existing production lines. The main objective of the industrial producer AGSIRA is to provide at least one new product to existing customers.
The research organizations will tackle together with AGSIRA the following issues established based on the needs identified at the industrial producer:
-design of a new production line to produce brewing yeast as feed through a new biotechnological process;
-obtaining a new product, having superior quality in comparison with the existing product in terms of composition, by optimizing the mixture between the yeast produced by the new technology with current processed spent brewing yeast;
-obtaining active brewing yeast (by freeze-drying and atomization);
-obtaining of derived products based on brewing yeast.
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DESIGN, EVALUATION AND MODELING OF DRUG RELEASE MECHANISM FOR NOVEL TOPICAL MULTIPARTICULATE DELIVERY SYSTEMS
Call name:
P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0813
2017
-
2018
Role in this project:
Key expert
Coordinating institution:
UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA
Project partners:
UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE - INCDTP BUCURESTI (RO)
Affiliation:
UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO)
Project website:
https://umfcd.ro/cercetare-si-dezvoltare/proiecte/proiecte-nationale/proectarea-evaluarea-si-modelarea-mecanismului-de-eliberare-a-medicamentului-pentru-noi-sisteme-multiparticulate-de-cedare-topica/
Abstract:
TOPMULTINOV project is a new and modern concept for the development of smart biomaterial supports usable in burned skin repair. Efficient regeneration of burned skin is still a clinical challenge, obtaining of an adequate drug release support being a top approach in the field of biomaterials. The general objective of this project consists of the design, evaluation and modeling of an anti-inflammatory drug release mechanism from topical multiparticulate systems that will ensure a controlled release for burns healing. As a novelty element of the project, ensuring a proper anti-inflammatory drug delivery from spongious collagen-based supports using different techniques that allow a gradual degradation of collagen support and a slow release of drug is mentioned. The vehicle formulation in the drug delivery sciences is a critical quality attribute which needs special attention for tailor made design to rationalize the system development. Thus, the project presents a new approach concerning the preparation of release supports like collagen-based spongious matrices with an anti-inflammatory drug incorporated in free form, in free and encapsulated form, and in encapsulated form respectively, to model and control its release rate. The results generated by the preparation, physico-chemical and morphological characterization as well as the in vitro studies of drug release and testing of the designed topical systems on animal model will be disseminated at conferences, in specialty articles, and by patent application. The pluridisciplinarity and complementarity of both teams provide high level of scientific/technical experiences to ensure a successful project achievement. TOPMULTINOV is perfectly integrated in the national and European strategies with respect to the impact on human health for improved health and life quality.
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Composed drug-impregnated biomaterials for postoperative complications
Call name:
69BM/2016
2016
-
2017
Role in this project:
Key expert
Coordinating institution:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE-I.N.C.D.T.P. BUCURESTI SUCURSALA BUCURESTI INSTITUTUL DE CERCETARE PIELARIE - INCALTAMINTE I.C.P.I.
Project partners:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE-I.N.C.D.T.P. BUCURESTI SUCURSALA BUCURESTI INSTITUTUL DE CERCETARE PIELARIE - INCALTAMINTE I.C.P.I. (); UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (); SPITALUL CLINIC DE URGENTA "SF.PANTELIMON" ()
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Project website:
Abstract:
Read more
INNOVATIVE THERAPEUTIC PRODUCTS WITH PROPHILACTIC AND CURATIVE ACTION FOR ZOO-VETERINARY SECTOR
Call name:
Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0953
2014
-
2017
Role in this project:
Key expert
Coordinating institution:
UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA
Project partners:
UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); UNIV.DE MEDICINA SI FARMACIE - CAROL DAVILA (RO); ASOCIATIA CENTRU DE CERCETARE STIINTIFICA IN DOMENIUL BIOCHIMIEI APLICATE SI BIOTEHNOLOGIEI (BIOTEHNOL) (RO); BIOING S.A. (RO); HOFIGAL EXPORT IMPORT SA (RO)
Affiliation:
Project website:
http://sanovet.fifim.ro/
Abstract:
Title: „INNOVATIVE THERAPEUTIC PRODUCTS WITH PROPHILACTIC AND CURATIVE ACTION FOR ZOO-VETERINARY SECTOR”
Acronym: SANOVET
Program: PARTNERSHIPS
Subprogram: “ Applied Collaborative Research Projects”
Domain 5 - Agriculture, food safety and security
Research thematic: 5.1.4. Methods, techniques and technologies for growth and diversification of animal production and fisheries, veterinary protection insurance Animal health is a concern for all European citizens. This concern stems from the public health, food safety and food security aspects, which are related to animal health but also to economic costs that animal disease outbreaks can trigger. This project uses a very common and a high economical and ecologically impact disease model like inflammation, as a paradigm for a conceptual and practical approach aimed to capitalize inexpensive and available resources.
The project goal is to improve the level of veterinary protection by developing a semi - solid phytoproduct from indigenous flora with topical application.
Main objectives that will ensure the achievement of project aim are:
1. Obtaining crops to exploit the curative potential of Anthriscus sp.;
2. Obtaining the phytocomplex;
3. Evaluating extracts pharmacological viability;
4. Obtaining an innovative phytoproduct .
The results of this research project will be materialized through:
1. Development and characterization of a herbal extract enriched in active ingredients with a complex chemical structure, non-toxic, based on original recipe obtained from association of fractionated extract with volatile oil from Anethum sp properly processed,
2. Highlighting the biologic activity, which plays a role in sustaining and accelerating the healing process by in vivo testing of herbal extract,
3. Creating a new topic semisolid phytoproduct.
The project addresses to a major agricultural problem in an interdisciplinary aggregate approach in order to achieve high yields results with a low economical input and a great environmental safety.
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Drug delivery systems based on natural polymers
Call name:
PNCDI II Capacities, Modul III, Bilateral Cooperation 502/18.03
2011
-
2012
Role in this project:
Key expert
Coordinating institution:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE-I.N.C.D.T.P. BUCURESTI SUCURSALA BUCURESTI INSTITUTUL DE CERCETARE PIELARIE - INCALTAMINTE I.C.P.I.
Project partners:
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU TEXTILE SI PIELARIE-I.N.C.D.T.P. BUCURESTI SUCURSALA BUCURESTI INSTITUTUL DE CERCETARE PIELARIE - INCALTAMINTE I.C.P.I. (); UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Project website:
Abstract:
Read more
Study of biological matrices interaction effects with some food on bioanalytical results variability
Call name:
42-100/2008
2008
-
2011
Role in this project:
Key expert
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Project website:
Abstract:
Read more
Development of a QSAR bioinformatic sistem for modeling of antitumoral and antirheumatic therapeutic agents in individualized therapies
Call name:
61-037/2007
2007
-
2010
Role in this project:
Project coordinator
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE IN DOMENIUL PATOLOGIEI SI STIINTELOR BIOMEDICALE "VICTOR BABES" (); UNIVERSITATEA BUCURESTI (); TERRASIGNA SRL ()
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Project website:
http://bioinfoqsar.asrc.ro/
Abstract:
Read more
Studies concerning the obtaining of transdermal hormonal systems using the lyposomes as transport and drug controlled release vectors
Call name:
61-024/2007
2007
-
2010
Role in this project:
Key expert
Coordinating institution:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA"
Project partners:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" (); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (); INSTITUTUL NATIONAL DE CERCETARE - DEZVOLTARE CHIMICO - FARMACEUTICA - I.C.C.F. BUCURESTI (); PHARMA SERV INTERNATIONAL SRL ()
Affiliation:
UNIVERSITATEA DE MEDICINA SI FARMACIE "CAROL DAVILA" ()
Project website:
Abstract:
Read more
FILE DESCRIPTION
DOCUMENT
List of research grants as project coordinator
List of research grants as partner team leader
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects
[T: 0.3883, O: 261]