BrainMap

Mrs. Elena Berteanu

Ph. D. Chemist

Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Researcher

Curriculum Vitae (20/09/2021)

Expertise & keywords

DEVELOPMENT OF INSTRUMENTS AND STRATEGIES FOR HIGHER VALORIZATION OF NATURAL RESOURCES FOR IMPROVING THEIR SUSTAINABLE EXPLOITATION IN BIO-INDUSTRIES AND CONSERVATION OF ECOSYSTEM FUNCTIONS Call name:
PN-III-1927 2019 - 2022

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE ()

Project website: http://www.incdsb.ro/en/proiecte/proiect-nucleu/

Abstract:

Obiectiv 1: CARACTERIZAREA SUBSTANTELOR SI PROCESELOR DE BAZA ALE SISTEMELOR BIOLOGICE SI A INTERELATIILOR LA NIVEL MOLECULAR SI/SAU CELULAR SI VALORIFICARII ACESTORA

19270101: Solutii integrate-versatile pentru concentrarea, caracterizarea si valorificarea fitocompusilor proveniti din (bio)resurse autohtone cu asigurarea principiilor dezvoltarii durabile (acronim BIO-AUP):

Extractia, caracterizarea si valorificarea unor fitoproduse cu valoare farmaceutica si cosmetica din clasa saponinelor prin procedee inovative.

Sistem bioanalitic multiparametru pentru determinarea compusilor cu structura fenolica cu activitate antioxidanta/antiinflamatorie si discriminarea celor cu activitate estrogenica/ antiestrogenica.

19270102: Tehnologii avansate de obtinere a unor noi biomateriale polimerice 3D pentru regenerarea tisulara, prin valorificarea subproduselor de origine animala si vegetala (acronim 3D-BIOMAT):

Obtinerea si caracterizarea fizico-chimica si biologica a unor biomateriale compozite si selectarea variantelor optime biomimetice matricei extracelulare dermice.

Caracterizarea biologica in vitro a biomaterialelor polimerice compozite prin teste pe celule specifice tesutului dermic.

19270103: Impactul schimbarilor climatice asupra microorganismelor si asupra organismului uman – Delta Dunarii in corelatie cu medii extreme: abordari practice si teoretice (ISC-MUD):

Analiza culturilor de microorganisme din habitatele studiate; analiza seturilor de probe de sânge prin citometrie în flux; studiul algoritmic al evoluţiei genomului ȋn relaţie cu aspecte cu diferite masuri.

Integrated system of bioremediation – biorefinering using halophyte species Call name: P 3 - SP 3.2 - Proiecte ERA.NET
ERANET-FACCE-SURPLUS-HaloSYS 2018 - 2021

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO); UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA (RO); IMT Atlantique (FR); Solutions Déchets et Développement Durable (FR); BIOTEN (PL); Institute of Natural Fibres and Medicinal Plants (PL)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Project website: http://www.incdsb.ro/p/halosys/index.html

Abstract:

The project proposes the cultivation of selected halophytes species on salt-affected soils with the aims of developing new value chains from obtained biomass.

The work will be conducted on the monitoring the degree of soil purification, the yield of biomass and seeds, and their chemical composition.

Obtained biomass will be investigated on the possibilities of extracting fibres to produce green composites, sugars for fermentative processes (bioethanol production), active biomolecules and micronutrients for developing new pharmaceutics and/or nutrceutics, oils from seeds for sustainable biodiesel synthesis. Waste resulted after extraction or pretreatment processes are further transformed into bio-based products (briquets, etc.). Process efficiency in terms of biomass production, salt-affected soil remediation, biomass conversion, materials and energy demand is the core activity for each involved step of the developed integrated technology targeting the optimal solution for ensuring overal sustainability.

Thus, HaloSYS project proposes an applied research work with a high knowledge transfer potential as alternative economic solution on bringing back into use for agricultural the farmland damaged by saltwater during coastal flooding, by the intensive agriculture practices or under the pressure of climate changes (aridisation phenomena).

Two SME’s are involved in life cycle assessment of biomass cultivation, soil quality management and biomass transformation technologies, as well as the evaluation of reducing the environmental footprint of agriculture. The project proposes the cultivation of selected halophytes species on salt-affected soils with the aims of developing new value chains from obtained biomass.

The work will be conducted on the monitoring the degree of soil purification, the yield of biomass and seeds, and their chemical composition.

Obtained biomass will be investigated on the possibilities of extracting fibres to produce green composites, sugars for fermentative processes (bioethanol production), active biomolecules and micronutrients for developing new pharmaceutics and/or nutrceutics, oils from seeds for sustainable biodiesel synthesis. Waste resulted after extraction or pretreatment processes are further transformed into bio-based products (briquets, etc.). Process efficiency in terms of biomass production, salt-affected soil remediation, biomass conversion, materials and energy demand is the core activity for each involved step of the developed integrated technology targeting the optimal solution for ensuring overal sustainability.

Thus, HaloSYS project proposes an applied research work with a high knowledge transfer potential as alternative economic solution on bringing back into use for agricultural the farmland damaged by saltwater during coastal flooding, by the intensive agriculture practices or under the pressure of climate changes (aridisation phenomena).

Two SME’s are involved in life cycle assessment of biomass cultivation, soil quality management and biomass transformation technologies, as well as the evaluation of reducing the environmental footprint of agriculture.

Enhancing immobilization enzymatic biotechnology of alkaline phosphatase in achievement some implantable materials performance Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-1337 2017 - 2018

Role in this project:

Coordinating institution: UNIVERSITATEA POLITEHNICA DIN BUCURESTI

Project partners: UNIVERSITATEA POLITEHNICA DIN BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU STIINTE BIOLOGICE (RO)

Project website: http://tihangratiela.github.io

Abstract:

During the last years, our research team studied collagen-chitosan membranes with and without silver proving their effect in enhancing antibacterial activity. The bactericidal action was more evident in the Escherichia coli case. The experimental study continued with the collagen-chitosan membranes and immobilized alkaline phosphatase (ALP), their haemolytic properties and cells viability being better than that registered on the simple collagen or chitosan membranes. Starting from our published data, this project represents a continuity of the biotechnological process for developing new membranes with immobilized protein that will be materialized as experimental TRL3 demonstrator. We intend to find a proper technique for improving the enzymatic activity of chitosan membranes for tissue engineering by adding different metal ions. The structural and morphological characteristics, mechanical properties, swelling degree, and contact angle of the membranes will be studied to find suitable formulation for use in therapy. The optimal concentration of Mg+2 to activate or inhibit the ALP activity and its influence on the cell adhesion and proliferation on obtained membranes will be achieved. The in vitro biodegradability using bacterial collagenase (Clostridium histolyticum) and haemocompatibility of the obtained membranes will be tested. Taking into account that incorporation of metal ions like Cu+2, Zn+2 or Ag+ can improve the antimicrobial property, we intend to find a specific metal ion for increasing the antimicrobial activity maintaining in the same time a high biocompatibility. At the end of this project we intend to submit a patent application.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects