BrainMap

Mr. Claudiu Tanaselia

PhD

Senior Researcher - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA

Researcher

Web of Science ResearcherID: B-5617-2011

Expertise & keywords

Innovative materials as dietary suppliments for healthcare Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-3373 2020 - 2022

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); INSTITUTUL REGIONAL DE GASTROENTEROLOGIE - HEPATOLOGIE PROF. DR. OCTAVIAN FODOR CLUJ-NAPOCA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: http://www.chem.ubbcluj.ro/romana/ANEX/cf/pcas/IMA_Health/index_IMA_Helath.htm

Abstract:

IMA-HEALTH project aims to validate at laboratory scale (TRL4), preparation methods (2) of poorly crystallized (HAP1) and highly crystallized (HAP2), sub-micron pure HAP and multi-substituted HAP (ms-HAP) with essential elements for bone regeneration. IMA-HEALTH project aims to validate at TRL4, the complex of HAP and ms-HAP with D3 and K2 vitamins, resulting (8) IMA-HEALTH dietary supplements to support the proper deposition of calcium into bone matrix, thereby maintaining skeletal integrity, and cardiovascular and arterial health. These supplements are expected to have a high effect on osteoblasts and endothelial cells related to the production of alkaline phosphatase, which is essential in regeneration of healthy new bone with impact on prevention and treatment of osteoporosis, and cardiovascular and arterial health. IMA-HEALTH is based on existing preparation methods for obtaining nano HAP with controlled size and shape of particles and crystallinity, at TRL2, previous research projects and Romanian patent. Main objective: •validation at lab scale of preparation methods/advanced materials based on sub-micron HAP as dietary supplements for healthcare. Specific objectives: •increasing the capacity of research organizations to develop innovative solutions validated in lab; •review of existing technical documentation; •development of sub-micron size HAP and hydroxyapatite/vitamins complexes; •optimization of IMA-HEALTH advanced materials EM; •demonstrating the utility and functionality of IMA-HEALTH, EM (TRL3); •validation of IMA-HEALTH, EM at lab scale (TRL4); •dissemination. Project end-products: validation at lab scale TRL4 of 2 preparation methods for HAP1 and HAP2, and 8 IMA-HEALTH dietary supplements: HAP, HAP/D3, HAP/K2, HAP/D3/K2, and ms-HAP, ms-HAP/D3, ms-HAP/K2, ms-HAP/D3/K2 poorly and highly crystallized - designed to replace imported dietary supplements at lower costs and in consequence, capable to compete on EU market, helping Romanian SMEs and economy.

Lanturi trofice in intuneric: diversitate si procese evolutive in pesteri Call name: P 4 - Proiecte Complexe de Cercetare de Frontieră
PN-III-P4-ID-PCCF-2016-0016-P 2019 - 2022

Role in this project: Key expert

Coordinating institution: INSTITUTUL ROMAN DE STIINTA SI TEHNOLOGIE

Project partners: INSTITUTUL ROMAN DE STIINTA SI TEHNOLOGIE (RO); UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: https://www.darkfoodincaves.com/

Abstract:

Caves are outstanding geomicrobiological, ecological, and evolutionary laboratories for the extreme conditions encountered in their deep passages: permanent absence of light, constant temperature, saturated air humidity, absence of primary producers, low nutrients, low biodiversity and short food chains. The study of caves as extreme habitats is relevant to life detection on extraterrestrial bodies and are of global importance because karst terrains (with caves) carries up to 25 % of drinking water. In addition, the new discoveries show that the microorganisms that inhabit caves may produce secondary metabolites that can be of value to humans. Understanding the cave microbial diversity and distribution in relationship to geochemical and other environmental conditions can be crucial in testing hypothesis and explaining processes, such as excellent conservation of bones, drawings and artifacts in caves, in finding new drugs and developing a genomic screening library for antibiotic production, or as proxy for food-starved sites in astrobiological researches. The metagenomic approach on the gut microbiota in cave invertebrates will indicate how much of the cave colonization and adaptation to a food-starved ecosystem has changed the symbiotic microbiome and is promoting diversification. It will also open the avenue to correlate the efficiency of substrate utilization and nutrient level with the structure and composition of microbial community in food-starved ecosystems. In the same time, metagenomics will possibly reveal the presence of novel genomes indicating new microbial taxa inhabiting cave-related mineral and/or invertebrate gut niches.

Nanovaccinal Approaches for Colon Cancer Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-0844 2020 - 2022

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU"

Project partners: UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO); INSTITUTUL REGIONAL DE GASTROENTEROLOGIE - HEPATOLOGIE PROF. DR. OCTAVIAN FODOR CLUJ-NAPOCA (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: https://nanovacol.wixsite.com/homero?lang=en

Abstract:

Colon cancer is a major cause of deaths worldwide, and it is expected to rise in the coming years. The development of nanoscale delivery of active substances represents an exciting and new approach to cancer immunoprophylaxis. General aim of the project would be to conjugate an immunogenic antigen to gold nanoparticles in order to promote major histocompatibility complex- involving antigen processing by antigen presenting cells. Tailored pharmaceutical formulation of by a specially designed capsule is going to be used, in order to offer optimal intestinal delivery of nano-bio celular vaccine.

Complex analytical methods to study Roman glazed ceramic from Dacian Kingdom for origin establishing of archaeological artifacts, imports/local production, at the Eastern border of Roman Empire Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2019-2373 2020 - 2022

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: https://icia.ro/glazex/

Abstract:

A complex set of analytical methods is proposed to study Roman glazed ceramic from Dacian Kingdom, for origin establishing of archaeological artifacts (imports or local production), at the Eastern border of Roman Empire. This new method could offer insights about the origin and the role of specific glazed ceramic artifacts in their respective setting, found at the eastern border of the Roman Empire. The proposed set consists of methods based on XRF, XRD, ICP-AES/MS techniques. Non-invasive XRF method can be used for initial assessment of chemical composition of the artifacts, but for better and more precise results this technique will be paired with more advanced analytical tools, like XRD, ICP-AES and ICP-MS. Ancient glazed ceramic contains high level of lead oxides and Pb isotopic ratio can be used to trace the origin of the artifact, a method that can be developed only on ICP-MS. The project offers a high level of expertise integration and complementary multidisciplinary approach. The coordinator already have experience in the field of analytical tools used on historical artifacts and lead isotopic ratio studies, a qualified personnel and access to required infrastructure to develop and validate the proposed set of methods, while the partner is contributing with qualified personnel with experience in archaeology and access to archaeological artifacts that weren’t previously tested with modern analytical techniques. The set proposed for validation at TRL4 level will be applied in archaeological/historical studies and can lead to improvements of important socio-economical aspects at the eastern border of the Roman Empire.

Integrated eco-technology for a selective recovery of base and precious metals in Cu and Pb mining by-products Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-ERANET-ERAMIN-MINTECO-2 2018 - 2021

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); Bureau de Recherches Géologiques et Minières (FR); Eskisehir Osmangazi University (TR); Mineral and Energy Economy Research Institute of the Polish Academy of Sciences (PL); Team Group Metals Sp. o.o. (PL); Ajelis SASA (FR)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: http://icia.ro/2018/07/27/minteco/

Abstract:

The MINTECO project aims to develop an integrated innovative, efficient and ecological technology for the recovery of base (Cu, Pb, Zn) and precious (Au, Ag) metals from Cu and Pb bearing mining waste (CLBM).

The project will allow the establishing of a global management methodology to treat historical mining sites and to reduce disposed volumes of metal-bearing waste. The MINTECO project will be tested on a selected case study on CLMB (3 mining sites identified in Romania, Poland and Turkey) by using pre-concentration methods (mineral processing) to separate non-useful compounds contained in the coarse fractions followed by leaching of concentrated fractions to dissolve all targeted metals and their recovery by innovative techniques (using dedicated synthesized organic molecules, thiosulfates and ionic liquids).

The main steps (pre-concentration/ leaching/ high grade metal recovery) will be studied in detail by research institutes to optimize first relevant process sequences. Then, a global coherent flowsheet will be proposed and the developed technologies will be subsequently validated by the industrial partners (SMEs) in the project at TR>4. Also, a final economic and environmental assessment will be performed.

The consortium gathers 8 partners from 4 countries (France, Romania, Poland and Turkey) and is composed of 3 research institutes,1 university, 1 public institution and 3 SMEs with complementary expertise.

Recovery of Precious Metals from Spent Catalysts by Supercritical CO2 Extraction Assisted by Polymers Call name: P 3 - SP 3.2 - Proiecte ERA.NET - COFUND
COFUND-ERANET-ERAMIN-SUPERMET 2018 - 2021

Role in this project: Key expert

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); École Nationale Supérieure de Chimie de Montpellier (FR); Innovation Fluides Supercritiques (FR); Heraeus Germany GmbH & Co. KG (DE); Fraunhoffer-Gesellschaft zur Förderung der Ange Wandten Forschung E.V. (DE)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: http://icia.ro/2018/07/27/supermet/

Abstract:

SUPERMET project proposes to explore an eco-friendly disruptive technology for the recycling of precious metals, especially palladium (Pd) and platinum (Pt), from spent catalysts, e.g. from petrochemistry catalysts, by extraction in supercritical CO2 (scCO2) thanks to complexing polymers bringing the insoluble precious metals into the scCO2 medium. Precious metals are used extensively in applications for catalysis not only in the petrochemistry, but also in the field of automotive (three way catalyst) and in the synthesis of fine chemicals. The scarcity of these metals poses a risk for the European countries which do not have this primary resource.

The pyrometallurgical and hydrometallurgical state of the art techniques developed for the recovery of these metals are energy-intensive, destructive, and generate large volumes of toxic effluents. With our proposed innovative recycling process, the catalytic support and the precious metal remain intact and can be reused as well as the used CO2 and polymer, so that there are no toxic effluents. Due to adjustable solvent properties of scCO2, the dissolved polymer-metal complex can be removed from the CO2 simply by depressurization. So, this new process is eco-efficient and solves a core problem of the state of the art processes.

The SUPERMET project, coordinated by the Charles Gerhardt Institute of Montpellier (ICGM, France), brings together partners from Germany, Romania and France: the Fraunhofer Institute for Chemical Technology (Fraunhofer ICT, Germany), Heraeus Deutschland GmbH & Co KG (Heraeus, Germany), the National Institute for Research and Development in Optoelectronics (INOE, ICIA Cluj-Napoca subsidiary, Romania) and the Supercritical Fluids Innovation Association (IFS, France).

Innovative technologies for advanced recovery of waste materials from IT and telecommunication equipment Call name: P 1 - SP 1.2 - Proiecte complexe realizate in consorții CDI
PN-III-P1-1.2-PCCDI-2017-0652 2018 - 2021

Role in this project: Partner team leader

Coordinating institution: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA

Project partners: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA (RO); UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); UNIVERSITATEA 1 DECEMBRIE 1918 ALBA IULIA (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); Institutul National de Cercetare-Dezvoltare pentru Chimie si Petrochimie - ICECHIM Bucuresti (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Project website: https://tradeit.utcluj.ro/

Abstract:

Although in 2016, at global level, the quantity of WEEE was over 45Mt (increasing 3-5% yearly), the estimated recycling rate only reaches 15-20%. Out of the total WEEE quantity, IT and telecommunication equipment waste (WEITT) represents c.a.15%, while printed circuit board waste, albeit only 3-6% of the total DEIT waste, concentrates 40% of the recoverable metals. At international level, the usual industrial technologies are mainly based on physical-mechanical and pyro-metallurgic procedures, but require high energy consumption and generate toxic by-products. At national level, reported research on WEITT processing is limited to the laboratory, while industrial processing agents only collect DEIT for export.

The consortium, composed of the Technical and Babeș-Bolyai universities of Cluj-Napoca, "1 Decembrie 1918" of Alba Iulia, Technical "Gheorghe Asachi" of Iași, INDO-INOE 2000 Research Institute for Analytical Instrumentation subsidiary ICIA and the National Institute for Research & Development in Chemistry and Petrochemistry, will elaborate, test and validate a complex of installations and optimised technologies for the integral reclaiming of WEITT materials, based on the following principles: 1) minimal energy consumption and reduced quantities of secondary waste, with reduced environmental impact, 2) smart disassembling and separation (mechanical, electrical and electrochemical) in order to obtain new or recycled materials with high purity and high economical value, 3) valorification of resulted plastic materials through non-polluting chemical technologies and their reintroduction in the production process, 4) development of a platform for monitoring environmental impacts and for learning reclaiming technologies for DEIT material 5) transfer of the developed technologies to companies in the Romanian reclaiming and recycling industry.

Lanturi trofice in intuneric: diversitate si procese evolutive in pesteri Call name: P 4 - Proiecte Complexe de Cercetare de Frontieră
PN-III-P4-ID-PCCF-2016-0016 2018 - 2019

Role in this project: Key expert

Coordinating institution: ACADEMIA ROMANA FILIALA CLUJ

Project partners: ACADEMIA ROMANA FILIALA CLUJ (RO); UNIVERSITATEA BABES BOLYAI (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE "IULIU HATIEGANU" (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: https://www.darkfoodincaves.com

Abstract:

Analytical eco-scale methods for the determination and speciation of Hg by UV photo-induced derivatization and detection using a fully-miniaturized experimental spectrometric system (ECOSPEC) Call name: P 2 - SP 2.1 - Proiect experimental - demonstrativ
PN-III-P2-2.1-PED-2016-0135 2017 - 2018

Role in this project: Key expert

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Affiliation: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Project website: http://www.chem.ubbcluj.ro/~edarvasi/Proiect2/index.html

Abstract:

The project aims at developing and validation of high sensitivity, excellent green analytical methods for the quantification of total Hg and its speciation as inorganic and organic forms using a fully-miniaturized instrumentation. Determination and speciation of Hg as Hg2+ and MeHg+ are based on ultrasound-assisted extraction in formic acid, photo-induced derivatization and detection by optical emission spectrometry using an existing experimental model that includes a capacitively coupled plasma microtorch and a low resolution microspectrometer. The starting point is TRL 3 (fully-miniaturized spectrometric system with capacitively coupled plasma -μCCP-OES- as excitation source) and the technological maturity is increased to TRL 4 by developing eco-scale laboratory methods validated for the determination and speciation of Hg with applicability in the environment and food control. The project is intended to be conducted in partnership by University Babes-Bolyai Cluj-Napoca as coordinator (CO-UBB) and Research Institute for Analytical Instrumentation Cluj-Napoca as partner (P1-ICIA). The project has a total duration of 18 months and is structured in 3 phases. The 1st phase is dedicated to establishing the optimal working conditions of the miniaturized analytical model UVCV-µCCP-OES as TRL 4. The 2nd phase includes activities related to evaluation of analytical performances, development and validation of the new laboratory methods for Hg determination and speciation and comparison with European legislation and classical methods based on thermal desorption atomic absorption spectrometry (TD-AAS), cold vapor atomic fluorescence and optical emission spectrometry in inductively coupled plasma source (CV-AFS and CV-ICP-AES). Within the 3rd phase it will be demonstrated the utility and analytical capability of the new eco-scale methods. Results will be disseminated in four ISI papers and national and international events.

Characteristics assessment of corn grown using organic fertilizers with manure from livestock farms compared with corn grown using chemical fertilizers Call name: P 2 - SP 2.1 - Cecuri de inovare
PN-III-P2-2.1-CI-2017-0142 2017 - 2017

Role in this project: Key expert

Coordinating institution: AGRO TURDEAN IMPEX SRL

Project partners: AGRO TURDEAN IMPEX SRL (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Project website: http://icia.ro/evapor/

Abstract:

EVAPOR project has as major goal the impact assessment of fertilizing technique that uses manure from livestock farms on corn harvest. The assessment will be realized by analyzing various parameters that reflect both the technological characteristics of corn as well characteristics related with food safety, all compared with corn grown using chemical fertilizers. The initial state of the project idea: experimental growing model, developed by company in 2016. Novelty degree of the project: is related to the assessment concept composed from complex elements all linked together, connecting both the biological and chemical risks arising with the use of fertilization techniques based on manure from livestock farms as well with the grown process as a whole. General objectives: properties assessment and comparison of corns grown using organic fertilizers with manure from livestock farms with corns grown using chemical fertilizers. Specific objectives: Assessment of technological characteristics of corns grown under the two conditions; Food safety assessment of corns grown under the two conditions; Soil micro- and macro elements content evaluation; Analysis, data processing and progress report including comparison of data resulted from corn grown using organic fertilizers with manure from livestock farms with corn grown using chemical fertilizers; Carbon footprint assessment considering both fertilizing technology; Expected results: through project implementation, it is expected to increase company turnover rate with approx. 3 %, improvement of product quality and job creation facilities.

Robotic assisted prostate biopsy, a high accuracy innovative method Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0647 2014 - 2017

Role in this project:

Coordinating institution: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA

Project partners: UNIVERSITATEA TEHNICA DIN CLUJ - NAPOCA (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE (U.M.F) Cluj-Napoca (RO); UNIVERSITATEA TRANSILVANIA BRASOV (RO); ELECTRONIC APRIL APARATURA ELECTRONICA SPECIALA S.R.L. (RO); INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

Affiliation:

Project website: http://www.cester.utcluj.ro/robocore/index.html

Abstract:

Prostate cancer is the most widely spread form of cancer, generally affecting men of age over 45. Several studies showed that 80% of the men over 70 had different forms of prostate cancer, most of them not being aware of that.

As in any disease, early diagnosis allows simpler curative actions, less patient trauma, better life expectancy and quality for the patient. Nevertheless, the diagnosis for prostate cancer is carried in the same way as it was performed 50 years ago. It involves a 12-core, transrectal ultrasound guided biopsy (TRUS). This technique is performed without knowing the exact 3D tumours location and it was proven that in 30% of the cases, it provides false-negative results. Magnetic resonance imaging (MRI) enables a better view of the prostate with clear tumour definition, but MRI guided biopsy can be achieved only with MRI compatible materials which make the procedure prohibitive. The current worldwide diagnosis technique for prostate cancer has some major drawbacks: low real-time image quality, blind biopsy and impossibility of registering the 3D location of the biopsy cores.

Early and correct diagnosis represents a critical priority and due to the current limitations it becomes the starting point of the ROBOCORE project. The consortium proposes the development of a system to achieve high accuracy ultrasound guided prostate biopsies through: ► the biopsy accuracy increase by the development of a robot capable to position the biopsy gun using the visual feedback from the TRUS probe, and ► the achievement of a software solution which performs the simulation, in virtual reality, of the prostate biopsy using MRI data.

The project aim is to develop a robotic system which combines the MRI capacity to identify malignant tissue and precisely define the biopsy targets with the accessibility and real-time capability of an ultrasound guided system. Using the virtual reality software the coordinates of the biopsy targets are identified, and using the robot the biopsy is performed with high accuracy. The system has two major components: ► a robot capable to perform the TRUS guided biopsy based on specific points of interest identified before, and ► an advanced software capable to perform the simulation in a virtual environment for the robotic assisted prostate biopsy.

Based on the defined aim and estimated results (Experimental Model of the robot capable of performing prostate biopsies + simulation software in virtual reality environment for the prostate biopsy + trained young scientists, 6 PhD students +patent +10 papers + 5 communications) ROBOCORE addresses the Domain 7–Innovative Materials, Processes and Products, and responds to the demands formulated in the research theme 7.3.2 Applied mechatronics; intelligent mechatronic products and systems.

The consortium is coordinated by the Technical University of Cluj-Napoca with renowned specialists in the field of parallel robots, and four institutional partners: University of Medicine and Pharmacy Cluj-Napoca with a team of urology doctors specialised in prostate cancer, University Transilvania of Brasov, which provides the software and virtual reality specialists, the Research Institute for Analytical Instrumentation with know-how in the development of medical devices and a private company, Electronic April Cluj-Napoca, specialised in medical apparatus development and commercialization. It must be stated that all the consortium members have previous experience and successful achievements in the field of medical robotics.

The end-product of ROBOCORE is an innovative complex system, which aims to provide accurate diagnosis in early cancer stages, enabling the proper therapy identification and an active surveillance of the tumours evolution which reduces the patient discomfort, provides him the right treatment at the right time and also enables proper follow-up after each evaluation or therapy stage.

Development of novel stereoselective biocatalysts for economic synthesis of chiral building blocks Call name: Joint Applied Research Projects - PCCA-2011 call, Type 1
PN-II-PT-PCCA-2011-3.1-1268 2012 - 2016

Role in this project:

Coordinating institution: UNIVERSITATEA BABES BOLYAI

Project partners: UNIVERSITATEA BABES BOLYAI (RO); UNIVERSITATEA TEHNICĂ "GHEORGHE ASACHI" IAŞI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Affiliation:

Project website: http://chem.ubbcluj.ro/~mtosa

Abstract:

Novel lipases with usual and opposite selectivity (anti-Kauzlauskas’ rule) immobilized in different forms, encapsulated whole cell ketoreductase systems with various stereoselectivity as "off-the-self" tools will be developed and different chiral building blocks will be prepared. We are planning to test 5-8 different immobilization techniques that may influence and enhance the productivity, stability, enantiomer selectivity of the applied biocatalyst.The application of enzyme immobilization technologies makes the bioconversation economically feasible and comparable to the synthetic solutions therefore increases the economical benefits. Finally, we plan to develop KITs containing several lipases immobilized in different forms. Development of the so called off-the-shelf products would change the habitual approach of synthetic chemists since the use of such a biocatalyst is easier than a synthetic chemical reaction with the required specifity and selectivity. These enzymes and enzyme products might be superior in synthetic biotransformations over the commercialized thermophilic fungal lipases with respest to the degree of enantiomer selectivity or direction/degree of enantiotopic selectivity.

Vulnerability of settlements and environment to floods in Romania within a global change context Call name: Joint Applied Research Projects - PCCA-2011 call, Type 1
PN-II-PT-PCCA-2011-3.1-1587 2012 - 2016

Role in this project:

Coordinating institution: INSTITUTUL DE GEOGRAFIE

Project partners: INSTITUTUL DE GEOGRAFIE (RO); INSTITUTUL NATIONAL DE HIDROLOGIE SI GOSPODARIRE A APELOR (RO); UNIVERSITATEA BUCURESTI (RO); INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Affiliation:

Project website: http://www.igar-vulmin.ro/

Abstract:

Over the last decade, under climate change and variability conditions, Romania recorded serious flood events (in 2005, 2006, 2010), being one of the most affected country at continental level. Moreover, public sector’s preparedness to flood hazards is almost missing, most of the protection measures being planned and implemented post-event. VULMIN project is dedicated at undertaking a comprehensive vulnerability assessment to flood hazards at national and local scales with the purpose of creating and providing practical scientific services to policy-makers. Within VULMIN two representative local scale studies (i.e. targeted areas in the low land of Timis-Bega system and the Bend Carpathians and Subcarpathians and the Moldavian Plateau) and a national level approach on vulnerability to flood hazards will be undertaking. Researchers from 4 Romanian institutions and different disciplines will identify flood-prone areas and assess their vulnerabilities, emphasizing on the linkages between flood events and their impact on communities, settlements, infrastructure and environment. The major outcomes of the vulnerability assessments consist in creating (spatial) scientific services (e.g. detailed standardized tools and digital maps of flood-prone areas and vulnerability zoning, adaptation measures), which will serve as policy and economic tools for vulnerability reduction. Furthermore, by identifying end-users’ requirements through active dialogue with national and local stakeholders, VULMIN project achieves a strong policy-oriented character, developing relevant connections between academics and decision-making processes. This is of increasing importance for Romania, as VULMIN result may lead to regulatory improvements, according to EU directives and strategies, particularly in the area of national risk transfer mechanisms in case of flood events.

2018 Winter Conference on Plasma Spectrochemistry. Plasma Spectrochemistry for Trace Element, Stable Isotope, and Elemental Speciation Analyses Call name: P 1 - SP 1.1 - Proiecte de mobilitate pentru cercetatori
PN-III-P1-1.1-MC-2017-0843 2017 -

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA

Project partners: INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD FILIALA INSTITUTUL DE CERCETARI PENTRU INSTRUMENTATIE ANALITICA CLUJ NAPOCA (RO)

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Evaluarea impactului activităților antropice (minerit, trafic, aglomerări urbane, schimbarea folosinţei solului) asupra contaminării unor râuri din Franţa şi România Call name: P 3 - SP 3.1 - Proiecte de mobilități, România-Franța (bilaterale)
PN-III-P3-3.1-PM-RO-FR-2016-0026 2016 -

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); Universitatea Paris Sud, Departamentul de Ştiinţa Pământului (FR)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

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Distribuția, cantitatea și calitatea resurselor de apă este influenţată de o gamă largă de activități antropice. Industria minieră și metalurgică, agricultura intensivă, expansiunea urbană şi modificările în folosinţa şi practicile de management al terenurilor sunt printre cele mai invazive activități antropice cu rol major în alterarea sistemului hidrografic şi a calităţii apei. Contaminarea cu metale a devenit o problemă globală din cauza persistenței și toxicității metalelor. Atât sedimentele cât și solurile au capacitatea de a acumula metalele, devenind astfel rezervoare pentru poluanţi. Prezenţa concomitentă a mai multor surse de contaminare în bazinele hidrografice face dificilă determinarea originii contaminanților. Pentru identificarea originii contaminanţilor şi a gradului de influență antropică sunt utilizați trasori izotopici specifici surselor și căilor de contaminare. Proiectul își propune să studieze impactul activităților antropice (minerit, trafic, aglomerări urbane, schimbarea folosinţei solului) asupra contaminării unor râuri din Franţa şi România, diferite în ceea ce privește dimensiunea bazinului, utilizarea terenurilor și a prezenţei activităților umane (minerit, agricultură, urbanizare) pentru a evalua capacitatea de rezistență a ecosistemelor la presiunea contaminanților.

Improving surface water quality assessment by semiquantitative and multielemental spectrometric methods Call name: P 3 - SP 3.1 - Proiecte de mobilități, România-Moldova (bilaterale)
PN-III-P3-3.1-PM-RO-MD-2016-0140 2016 -

Role in this project: Project coordinator

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); Universitatea Academiei de Stiinte a Moldovei (UnASM) (MD)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Project website:

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Proiectului propune dezvoltarea și ajustarea unei metode semicantitative noi pentru analiza apelor de suprafață, metodă care va putea fi ulterior aplicată în laboratoarele de mediu. Analizele semicantitative oferite de spectrometria de masă cu plasmă cuplată inductiv vor oferi informații complete despre probă din punct de vedere al conținutului de metale grele într-un timp scurt și fără necesitatea acoperii întregului spectru de masă cu soluții de calibrare. Analize complementare, efectuate prin tehnici precum ICP-AES și AAS vor valida rezultatele obținute prin metoda semicantitativă prin ICP-MS și vor ajuta la îmbunătățirea calibrării, dar și la dezvoltarea de noi metode eficiente, rapide și mai puțin costisitoare. Ca studii de caz vor fi analizate probe de apă din râurile Someș (România), Bîc (Republica Moldova) și Prut (granița româno-moldavă) de către ambele echipe implicate în proiect. Colaborarea celor două echipe în cadrul proiectului va îmbunătăți performanțele tehnicilor analitice folosite pentru analizele de mediu, atât în cadrul echipei moldave, cât și în ceea ce privește echipa românească. Parteneriatul va facilita o comunicare mai eficientă între cele două echipe și o cunoaștere mai detaliată a rezultatelor obținute de fiecare partener în acest domeniu. Realizarea cercetărilor propuse va permite dezvoltarea resurselor umane prin formarea tinerilor cercetători în domeniul chimiei analitice și a tehnicilor de analiză spectrometrice moderne.

Human health risk assessment of some contaminants in local foods of plant and animal origin Call name: P 3 - SP 3.1 - Proiecte de mobilități, România-Moldova (bilaterale)
PN-III-P3-3.1-PM-RO-MD-2016-0047 2016 -

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); INSTITUTUL DE GENETICA, FIZIOLOGIE SI PROTECȚIE A PLANTELOR AL ASM RM (MD)

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Contaminarea mediului reprezintă un pericol deosebit şi un impediment major în dezvoltarea unei societăţi durabile, cu consecinţe negative directe asupra calităţii mediului şi implicit asupra omului. Metalele grele și poluanții organici persistenți sunt foarte toxici și bioacumulativi, chiar și în cantități mici. Alături de aer și apă, alimentele constituie factori de mediu esențiali pentru asigurarea bunei desfășurări a tuturor proceselor vitale. Contaminanții ajung în alimente pe căi naturale, ca rezultat al activităților umane sau prin contaminarea în timpul preparării/procesării și stocării. În ultimii ani, s-au intensificat studiile în vederea determinării contaminanţilor chimici din alimente şi evaluării riscului acestora asupra sănătății umane, cu importanţă majoră pentru planificarea şi desfășurarea activităţilor preventive. Proiectul de cooperare bilaterală CONTALI se dorește a fi un răspuns la toate acestea, prin: -evaluarea nivelului de contaminare cu metale grele și pesticide organofosforice a produselor alimentare locale frecvent consumate, de origine vegetală şi animală; -evaluarea riscului pentru sănătatea umană asociat acestor contaminanți; -metode de analiză performante, rapide și economice de determinare a metalelor grele din produse alimentare de origine vegetală și animală; -consolidarea cooperării ştiinţifice şi activităţi comune de cercetare ca suport fezabil la elaborarea de proiecte științifice comune în cadrul Programului Orizont 2020 al UE.

Change in redox status and Expression of Stress related Genes in Spirulina (Arthrospia) under oxidative stress condition Call name: P 3 - SP 3.1 - Proiecte de mobilități, România-Moldova (bilaterale)
PN-III-P3-3.1-PM-RO-MD-2016-0056 2016 -

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); Institutul de Microbiologie și Biotehnologie (MD)

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Spirulina (Arthrospira) platensis este unul dintre cele mai bine studiate și mai sigure obiecte biotehnologice, avizate pentru uz uman, fiind sursă prețioasă aminoacizi esențiali, și compuși cu proprietăți biologice performante.

Scopul prezentului proiect constă în evaluarea modificării statutului redox şi a expresiei genelor legate de stres la Spirulina (Arthrospia) în condiţii de stres oxidativ. Obiectivele ştiinţifice: ►Dezvoltarea metodelor analitice pentru evaluarea statutului redox şi a expresiei genelor ►Elaborarea procedeelor de inducere a stresului oxidativ ►Determinarea impactului în condiţii de stres oxidativ asupra Spirulinei ►Diseminarea pe scară largă a rezultatelor. Rezultatele obţinute vor favoriza dezvoltarea de noi colaborări internaţionale în vederea participării la viitoare competiții de proiecte la nivel internațional, precum şi creșterea numărului de co-publicații.

Pe durata realizării proiectului vor fi utilizate următoarele modele experimentale și metode de cercetare: modelul biotehnologic de creștere a spirulinei în cultură statică în condiții de laborator și de producere; metode spectrofotometrice de cuantificare a radicalilor liberi și a produselor finale de degradare oxidativă a lipidelor și de determinare a capacității antiradicalice nespecifice și specifice a biomasei de spirulină; metoda PCR pentru aprecierea nivelului de expresie a genelor asociate cu stresul; LC-MS-MS/FPLC pentru determinarea produselor de expresie.

Comparison of metal pollution patterns in soils from industrial areas of France and Romania Call name: Programul de actiuni Integrate Romania-Franta (bilaterale)
PN-II-CT-RO-FR-2014-2-0021 2014 -

Role in this project:

Coordinating institution: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD

Project partners: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO); Géosciences Environnement Toulouse (FR)

Affiliation: INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU OPTOELECTRONICA INOE 2000 INCD (RO)

Project website:

Abstract:

Soil is the major receptor for metals generated by anthropogenic activities. Due to metals toxicity and persistence, soil contamination with metals is an important issue, especially in industrial areas, where emissions, wastewaters and wastes with high metal loads act as the main pollution vectors. The project’s main objective is the comparative evaluation of soil contamination with metals in industrial areas of France and Romania, using multi-elemental and isotopic fingerprinting. The project will allow the development of pollution fingerprinting, identification of pollution tracers, source apportionment of polluting metals and establishment of a database with pollution sources fingerprints. The consortium consists of two research institutions with expertise in the assessment of environmental pollution by metals. Project results will allow the increase of the expertise of the team members in advanced analytical techniques for the determination of stable isotopes will underpin the development of new collaborations and will help increase the visibility of research in the two countries.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator
List of research grants as partner team leader
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects