BrainMap

Adelina Antonia Andelescu

- INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU"

Researcher

Expertise & keywords

Luminescent Organic-Inorganic Hybrid Water Soluble Supramolecular Architectured Nanoplaforms for Theranostics Call name: P 1 - SP 1.1 - Proiecte de cercetare Postdoctorală - PD-2021
PN-III-P1-1.1-PD-2021-0427 2022 - 2024

Role in this project:

Coordinating institution: INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU"

Project partners: INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU" (RO)

Affiliation:

Project website: https://acad-icht.tm.edu.ro/wp/eng/?page_id=1356

Abstract:

In the framework of synthesising new advanced functional materials, the scope of the project is to obtain new luminescent organic-inorganic hybrid supramolecular architectured water soluble nanoplatforms (LOISA) carrying luminescent d-block transition metal complexes (TMCs) based on Zn(II) and Pt(II) metal centres with terpyridine (tpy) ligands functionalized with selenium anchors and hydrophilic ancillary ligands (HL). The nanoplatforms are designed to have dual simultaneous function (theranostic agents) combining diagnosis (sensitive emission properties) and treatment (carriers of potential anticancer drugs - TMCs). The research approach is a continuation of the work developed by the project leader (PL) during her PhD. The originality and novelty of the project consist in the use of selenide linkers for a successful obtainment with high yields of LOISA, fructifying the vast knowledge of the Mentor in the field of organochalcogen chemistry. Another key novelty highly useful for future applications in biological fields is the induction of water solubility using hydrophilic ligands. The successful obtainment of LOISA will bring fundamental advancements in the main project field PE5_6, and in complementary scientific domains like intelligent materials – self-assembled materials PE5_8, coordination chemistry PE5_9, supramolecular chemistry PE5_16.

ICT - Centru interdisciplinar de specializare inteligentă în domeniul chimiei biologice RO-OPENSCREEN Call name: Proiecte de infrastructuri de cercetare pentru instituţii publice de CD/ universităţi - PENTRU REGIUNI MAI PUTIN DEZVOLTATE - LDR (fara Bucuresti - Ilfov)
127952 2020 - 2023

Role in this project: Key expert

Coordinating institution: INSTITUTUL DE CHIMIE "CORIOLAN DRAGULESCU" (FOSTUL INSTITUT DE CHIMIE TIMIŞOARA AL ACADEMIEI ROMÂNE)

Project partners: INSTITUTUL DE CHIMIE "CORIOLAN DRAGULESCU" (FOSTUL INSTITUT DE CHIMIE TIMIŞOARA AL ACADEMIEI ROMÂNE) (RO)

Affiliation: INSTITUTUL DE CHIMIE "CORIOLAN DRAGULESCU" (FOSTUL INSTITUT DE CHIMIE TIMIŞOARA AL ACADEMIEI ROMÂNE) (RO)

Project website:

Abstract:

Advanced Self-Assembled Hybrid Nanoarrays with Controlable Inter-nanoelectrode Positions for Ultrasensitive Sensing in Medical Applications Call name: P 4 - Proiecte de Cercetare Exploratorie, 2020
PN-III-P4-ID-PCE-2020-1958 2021 - 2023

Role in this project: Key expert

Coordinating institution: INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU"

Project partners: INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU" (RO)

Affiliation: INSTITUTUL DE CHIMIE "CORIOLAN DRĂGULESCU" (RO)

Project website: https://acad-icht.tm.edu.ro/wp/eng/?page_id=1003

Abstract:

The present project aims to explore the structure – property - electrochemical function relationship of a complex matrix nanoplatform based on metallomesogens (MMs) as precursors for in-situ generation of randomized/ordered metal oxide (MOx) nanoelectrode array (MONA) for the fabrication of electrochemical high performance hybrid sensors. The control of the size, the shape and the inter-nanoelectrode separation will be performed by controlling the supramolecular organisation in the liquid crystalline state of the coordination complex used to modify the nanostructured electrode. Based on the fundamental knowledge acquired, the development of a Wireless Electronics-integrated Portable ultrasensitive Sensors (WEPS) for real-time non-invasive biomedical applications will be also explored by using different possible scenarios and designs. The project will be realized using the multidisciplinary and interdisciplinary expertise of renowned scientists together with young scientists and students following an integrative approach for an in-depth understanding of surface and interface chemistry and charge transport, as reference for opening other applied research areas.

Selective decontamination of colored wastewaters by magnetic nanocomposites Call name: Projects for Young Research Teams - RUTE -2014 call
PN-II-RU-TE-2014-4-1319 2015 - 2017

Role in this project: Key expert

Coordinating institution: INSTITUTUL DE CHIMIE

Project partners: INSTITUTUL DE CHIMIE (RO)

Affiliation: INSTITUTUL DE CHIMIE (RO)

Project website: http://acad-icht.tm.edu.ro/granturi/SeWaGe-MaGNano.html

Abstract:

The project approaches the problem of wastewater treatment aimed mainly to develop a high performance wastewater treatment system based on magnetite/carbon nanocomposites (NMC) as adsorbents. In this sense, the project aims synthesis and detailed characterization of new type of tailored-made magnetic nanoparticles functionalized with various groups such as: amino, carboxyl, hydroxyl, by means of combustion. The performance of magnetic composites will be tested for selective adsorption of dyes and metal ions from model and industrial wastewaters.

The optimization of adsorption processes will be performed by taking into account variables such as pH, temperature, and contact time. The adsorption studies will be performing for removal of dyes and metal ions in batch and continuous system, for mono- and multi-component solutions. The elucidation of adsorption mechanism will be performed. The reusability of NMC will be investigated in the repeated adsorption–desorption cycle.

Advanced recovery of useful materials from used catalyst wastes Call name: Joint Applied Research Projects - PCCA 2013 - call
PN-II-PT-PCCA-2013-4-0612 2014 - 2017

Role in this project: Key expert

Coordinating institution: INSTITUTUL DE CHIMIE

Project partners: INSTITUTUL DE CHIMIE (RO); PRO AIR CLEAN ECOLOGIC S.A. (RO); INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU ECOLOGIE INDUSTRIALA - ECOIND (RO); UNIVERSITATEA DE MEDICINA SI FARMACIE " VICTOR BABEŞ " TIMISOARA (RO)

Affiliation: INSTITUTUL DE CHIMIE (RO)

Project website: http://acad-icht.tm.edu.ro/granturi/REMACAT.html

Abstract:

Responsible management of wastes coming from technological processes is a great priority highlighted by the internal and European legislation. According to the European legislation this means responsible management of chemical wastes by each member state, and also, of all the factors implied the life cycle of all products, and an important economical opportunity as well.

This project has, as main goal, the environment protection by recycling used complex catalysts having as support and flowing agent organic solvents in the purpose of reducing the emissions of heavy metals in environment and reducing pollution with aromatic organic materials. The second major objective, the economical one, deals with the valorisation of metallic compounds as advanced materials for the use in water cleaning systems and the advanced recycling of used solvents and water by means of green chemistry principles. The object of the project refers to the used complex catalyst CuAlCl4*toluene resulted from the COSORB processes, according to the following: separation and purification of toluene, recovery of copper as metallic powder, valorisation of aluminum(III) as flocculation agent in the cleaning water systems. The last objective also means the valorisation of the existent iron wastes at industrial partner, in order to obtain a complex flocculation agent Al(III)-Fe(III).

The objective of the project is placed in the research frame 3. Environment – 3.2.5. Theme Technologies for treating hazardous wastes. According to this theme, we accomplish:

- Chemical evaluation of the used complex catalyst – as waste;

- Establishing a unitary technology starting from the used complex catalyst and iron waste and providing reusable materials as an outcome.

The following steps are involved:

- setting up the separation and purification technology for the organic and inorganic components;

- elaborating the technology of metallic components valorisation as advanced materials;

- elaborating the technology of inorganic components valorisation as flocculation agents for water treatment;

- the design and making of the industrial plant;

- technological processes implementation;

- toxicological control and pollution impact on each step and products.

The novelty of the proposed solution refer to: (i) setting up a unitary technological flow; (ii) selection of the most adequate chemical methods for elaboration of economical and efficient technologies following the principles of green chemistry; (iii) obtaining high purity materials (toluene, copper, flocculation agents); (iv) obtaining a composite flocculation agent (also the technology) Al(III)-Fe(III) within the desired proportions and synergic effect;(v) the toxicological and pollution control of each technological step in order to control the ecological risk.

Participative management will be implemented in the partners’ relationship, the coordination of the activities and the relation with the Contractual Authority. Structured into 5 chapters, corresponding also to the 5 working packages, this proposal is the outcome of the project management activities to which all partner entities have contributed.

The impact of the project, generated by its results, is found in the environment protection (reducing the metal and hydrocarbon pollution risk), technical/scientific (elaboration of technologies and toxicological and chemical analysis systems), economical (efficiency/costs ratio) and social (eliminating the risk regarding people’s health and creating new work places) aspects.

Solving this multi-, inter- and transdisciplinary project implies activities specific to industrial research supported on fundamental knowledge and activities. The results obtained in the frame of this project is a unitary technological process and corresponding industrial plant implemented at the industrial partner and will be disseminated by two patents, communications, publications both on national and international levels and by organizing one workshop.

FILE DESCRIPTION	DOCUMENT
List of research grants as project coordinator or partner team leader
Significant R&D projects for enterprises, as project manager
R&D activities in enterprises
Peer-review activity for international programs/projects